Adenoid Hyperplasia in a Patient With a Rare Type of Hyper Immunoglobulin M Syndrome Due to CD40 Deficiency

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BAHRAMI AHMAD; SOLTANI ZAHRA; FAZLOLLAHI MOHAMMAD REZA; Rahmani Farzaneh; HOUSHMAND MASSOUD; Mazinani Marzieh; REZAEI NIMA

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Journal: ACTA MEDICA IRANICA Year:2018 | Volume:56 | Issue:12 Page(s): 811-814

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Title

Adenoid Hyperplasia in a Patient With a Rare Type of Hyper Immunoglobulin M Syndrome Due to CD40 Deficiency

Author(s)

Keywords

Hyper-immunoglobulin M syndrome

CD40

HIGM type 3

Lymphoid hyperplasia

Abstract

CD40 deficiency yield to an autosomal recessive subtype of Hyper-immunoglobulin M syndrome (HGIM type 3), presenting with an almost identical clinical picture to X-linked CD40L deficiency (HIGM type 1) with profound T-cell dysfunction yielding to opportunistic infections as well as neutropenia, autoimmunity, and malignancy. We presented a girl with recurrent upper respiratory tract infections and Lymphoid hyperplasia which was diagnosed with type 3 hyper IgM syndrome due to CD40 gene mutation. Otitis media with opportunistic germs and no evidence for an X-linked pattern of inheritance were diagnostic keys to type 3 hyper IgM syndrome in our patient.

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APA: Copy

BAHRAMI, AHMAD, SOLTANI, ZAHRA, FAZLOLLAHI, MOHAMMAD REZA, HOUSHMAND, MASSOUD, Mazinani, Marzieh, & REZAEI, NIMA. (2018). Adenoid Hyperplasia in a Patient With a Rare Type of Hyper Immunoglobulin M Syndrome Due to CD40 Deficiency. ACTA MEDICA IRANICA, 56(12), 811-814. SID. https://sid.ir/paper/279125/en

Vancouver: Copy

BAHRAMI AHMAD, SOLTANI ZAHRA, FAZLOLLAHI MOHAMMAD REZA, HOUSHMAND MASSOUD, Mazinani Marzieh, REZAEI NIMA. Adenoid Hyperplasia in a Patient With a Rare Type of Hyper Immunoglobulin M Syndrome Due to CD40 Deficiency. ACTA MEDICA IRANICA[Internet]. 2018;56(12):811-814. Available from: https://sid.ir/paper/279125/en

IEEE: Copy

AHMAD BAHRAMI, ZAHRA SOLTANI, MOHAMMAD REZA FAZLOLLAHI, MASSOUD HOUSHMAND, Marzieh Mazinani, and NIMA REZAEI, “Adenoid Hyperplasia in a Patient With a Rare Type of Hyper Immunoglobulin M Syndrome Due to CD40 Deficiency,” ACTA MEDICA IRANICA, vol. 56, no. 12, pp. 811–814, 2018, [Online]. Available: https://sid.ir/paper/279125/en

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