CHROMOSOMAL ABERRATIONS IN LYMPHOCYTES
OF INDIVIDUALS WITH CHRONIC EXPOSURE TO
GAMMA RADIATION

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

HEJAZI A.A.; HEJAZI P.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: ARCHIVES OF IRANIAN MEDICINE Year:2002 | Volume:5 | Issue:1 Page(s): 32-36

Download Full-Text

View:

378

Download:

283

Cites:

Information Journal Paper

Title

CHROMOSOMAL ABERRATIONS IN LYMPHOCYTES OF INDIVIDUALS WITH CHRONIC EXPOSURE TO GAMMA RADIATION

Author(s)

HEJAZI A.A. | HEJAZI P. | Issue Writer Certificate

Keywords

OCCUPATIONAL RADIATION EXPOSURE • NUCLEAR MEDICINE • CHROMOSOMAL ABERRATIONS • LYMPHOCYTES

Abstract

Background-Apart from direct dose assessment of radiation exposure, analysis of chromosomal aberrations using the standard method has been widely used in monitoring the cytogenetic effects of long-term occupational radiation exposure. Chromosomal damage in human somatic cells may serve as an early indicator of hazard, thus enabling prevention of adverse effects. Methods-The frequency of chromosomal aberrations were evaluated in the peripheral blood lymphocytes obtained from 51 nuclear medicine technologists (NMT) who were exposed to chronic doses of gamma rays and 15 healthy controls. Lymphocytes were cultured in RPMI-1640 and metaphase plates were prepared using standard cytogenetic method. One hundred mitoses were analyzed for the presence of chromosomal aberrations for each sample. Radiation exposure was measured using film badge and thermoluminescent dosimeter (TLD). Results-The monthly dose equivalent received by the nuclear medicine technologists was between 0.03 to 2.80 mSv as measured by TLD and film badges. The frequencies of all types of aberrations (gaps, breaks and dicentrics) in exposed subjects were higher than those observed in the control group (p<0.0001). This study showed a linear dose-response relationship for total chromosomal deletions and dicentrics (p< 0.0001). Conclusion-The findings in this study are important, because radiation workers who have been exposed to doses well below accepted standards for exposure to radiation also show elevated levels of all types of chromosomal aberrations. Therefore, these results might imply that workers receiving very low doses of radiation during a long period of time could be considered as individuals at risk.

Cites

No record.

References

No record.

Cite

APA: Copy

HEJAZI, A.A., & HEJAZI, P.. (2002). CHROMOSOMAL ABERRATIONS IN LYMPHOCYTES OF INDIVIDUALS WITH CHRONIC EXPOSURE TO GAMMA RADIATION. ARCHIVES OF IRANIAN MEDICINE, 5(1), 32-36. SID. https://sid.ir/paper/279919/en

Vancouver: Copy

HEJAZI A.A., HEJAZI P.. CHROMOSOMAL ABERRATIONS IN LYMPHOCYTES OF INDIVIDUALS WITH CHRONIC EXPOSURE TO GAMMA RADIATION. ARCHIVES OF IRANIAN MEDICINE[Internet]. 2002;5(1):32-36. Available from: https://sid.ir/paper/279919/en

IEEE: Copy

A.A. HEJAZI, and P. HEJAZI, “CHROMOSOMAL ABERRATIONS IN LYMPHOCYTES OF INDIVIDUALS WITH CHRONIC EXPOSURE TO GAMMA RADIATION,” ARCHIVES OF IRANIAN MEDICINE, vol. 5, no. 1, pp. 32–36, 2002, [Online]. Available: https://sid.ir/paper/279919/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops