RISK FACTORS FOR NEURAL TUBE DEFECTS: A STUDY AT UNIVERSITY-AFFILIATED HOSPITALS IN TEHRAN

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NILI F.; JAHANGIRI M.

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Journal Paper

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Journal: ARCHIVES OF IRANIAN MEDICINE Year:2006 | Volume:9 | Issue:1 Page(s): 20-25

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Title

RISK FACTORS FOR NEURAL TUBE DEFECTS: A STUDY AT UNIVERSITY-AFFILIATED HOSPITALS IN TEHRAN

Author(s)

NILI F. | JAHANGIRI M. | Issue Writer Certificate

Keywords

NEURAL TUBE DEFECTS • RISK FACTOR

Abstract

Background: Neural tube defects have a complex and imperfectly understood etiology involving both genetic and environmental factors. In this case-control study, we tried to determine the association of known risk factors for neural tube defects in patients referred to universityaffiliated hospitals with neurosurgical services in the city of Tehran.Methods: Risk factors were assessed in-person through interviews with infants’ mothers. We found 192 neural tube defect cases. One hundred and ninety-three apparently normal babies were randomly selected from the same hospitals to serve as control cases.Results: Maternal age of less than 18 years (P = 0.02), female sex of the child (P = 0.01), birth in spring and summer seasons (P = 0.001), history of not using folic acid (P = 0.001), less than 5 prenatal visits (P = 0.001), and poverty (P = 0.02) were the most important risk factors for neural tube defects. Logistic regression analysis of these risk factors confirmed these correlations. A negative history of consuming folic acid had the most significant statistical correlation with these malformations.Conclusion: Poor quality diets were an important environmental risk factor in this study.

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APA: Copy

NILI, F., & JAHANGIRI, M.. (2006). RISK FACTORS FOR NEURAL TUBE DEFECTS: A STUDY AT UNIVERSITY-AFFILIATED HOSPITALS IN TEHRAN. ARCHIVES OF IRANIAN MEDICINE, 9(1), 20-25. SID. https://sid.ir/paper/280057/en

Vancouver: Copy

NILI F., JAHANGIRI M.. RISK FACTORS FOR NEURAL TUBE DEFECTS: A STUDY AT UNIVERSITY-AFFILIATED HOSPITALS IN TEHRAN. ARCHIVES OF IRANIAN MEDICINE[Internet]. 2006;9(1):20-25. Available from: https://sid.ir/paper/280057/en

IEEE: Copy

F. NILI, and M. JAHANGIRI, “RISK FACTORS FOR NEURAL TUBE DEFECTS: A STUDY AT UNIVERSITY-AFFILIATED HOSPITALS IN TEHRAN,” ARCHIVES OF IRANIAN MEDICINE, vol. 9, no. 1, pp. 20–25, 2006, [Online]. Available: https://sid.ir/paper/280057/en

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