مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

429
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

462
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

AUTOLOGOUS TRANSPLANTATION OF BONE MARROW-DERIVED MONONUCLEAR AND CD133+ CELLS IN PATIENTS WITH DECOMPENSATED CIRRHOSIS

Pages

  12-17

Abstract

 Background: Cirrhosis, the end stage of progressive hepatic fibrosis, is characterized by distortion of the hepatic architecture and the formation of regenerative nodules. LIVER transplantation is one of the few available therapies for such patients. However, due to a severe shortage of organ donors, surgical complications, transplant rejection and the high cost of this procedure much interest has focused on research to nd new treatment modalities for this disease. There is accumulating evidence for the contribution of BONE MARROW stem cells to participate in LIVER regeneration.Methods: Here we report on six patients with end stage LIVER disease who were subjected to intraportal administration of autologous BONE MARROW-derived CD133+in comparison to mononuclear cells in short-term (6 months) and long-term (24 months) follow up.Results: There were no adverse effects in any of the patients during the short-and long-term follow up period. Moreover, there were no signicant alterations of LIVER function parameters, LIVER enzymes, serum albumin, creatinine, serum bilirubin and/or LIVER volume after transplantation of both types of autologous cells in these patients.Conclusion: Our study has shown both the safety and feasibility of this type of LIVER cell therapy and may be a bridge to LIVER transplantation.The trial was registered with NIH clinical trials (www.clinicaltrials.gov) as identier: NCT00713934.

Cites

  • No record.
  • References

  • No record.
  • Cite

    APA: Copy

    NIKEGHBALIAN, SAMAN, POURNASR, BEHSHAD, AGHDAMI, NASSER, RASEKHI, ALIREZA, GERAMIZADEH, BITA, HOSSEINI ASL, SEYED MOHAMMAD KAZEM, RAMZI, MANI, KAKAEI, FARZAD, NAMIRI, MEHRNAZ, MALEKZADEH, REZA, VOSOUGH DIZAJ, AHMAD, MALEK HOSSEINI, SEYED ALI, & BAHARVAND, HOSSEIN. (2011). AUTOLOGOUS TRANSPLANTATION OF BONE MARROW-DERIVED MONONUCLEAR AND CD133+ CELLS IN PATIENTS WITH DECOMPENSATED CIRRHOSIS. ARCHIVES OF IRANIAN MEDICINE, 14(1), 12-17. SID. https://sid.ir/paper/280716/en

    Vancouver: Copy

    NIKEGHBALIAN SAMAN, POURNASR BEHSHAD, AGHDAMI NASSER, RASEKHI ALIREZA, GERAMIZADEH BITA, HOSSEINI ASL SEYED MOHAMMAD KAZEM, RAMZI MANI, KAKAEI FARZAD, NAMIRI MEHRNAZ, MALEKZADEH REZA, VOSOUGH DIZAJ AHMAD, MALEK HOSSEINI SEYED ALI, BAHARVAND HOSSEIN. AUTOLOGOUS TRANSPLANTATION OF BONE MARROW-DERIVED MONONUCLEAR AND CD133+ CELLS IN PATIENTS WITH DECOMPENSATED CIRRHOSIS. ARCHIVES OF IRANIAN MEDICINE[Internet]. 2011;14(1):12-17. Available from: https://sid.ir/paper/280716/en

    IEEE: Copy

    SAMAN NIKEGHBALIAN, BEHSHAD POURNASR, NASSER AGHDAMI, ALIREZA RASEKHI, BITA GERAMIZADEH, SEYED MOHAMMAD KAZEM HOSSEINI ASL, MANI RAMZI, FARZAD KAKAEI, MEHRNAZ NAMIRI, REZA MALEKZADEH, AHMAD VOSOUGH DIZAJ, SEYED ALI MALEK HOSSEINI, and HOSSEIN BAHARVAND, “AUTOLOGOUS TRANSPLANTATION OF BONE MARROW-DERIVED MONONUCLEAR AND CD133+ CELLS IN PATIENTS WITH DECOMPENSATED CIRRHOSIS,” ARCHIVES OF IRANIAN MEDICINE, vol. 14, no. 1, pp. 12–17, 2011, [Online]. Available: https://sid.ir/paper/280716/en

    Related Journal Papers

  • No record.
  • Related Seminar Papers

  • No record.
  • Related Plans

  • No record.
  • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button