CONGENITAL ANOMALIES IN INFANTS CONCEIVED BY ASSISTED REPRODUCTIVE TECHNIQUES

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MOZAFARI KERMANI RAMIN; NEDAEIFARD LEILA; NATEGHI MOHAMMAD REZA; SHAHZADEH FAZELI ABOLHASSAN; AHMADI EBRAHIM; OSIA MOHAMMAD ALI; JAFARZADEHPOUR EBRAHIM; NOURI SOUDABEH

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Journal: ARCHIVES OF IRANIAN MEDICINE Year:2012 | Volume:15 | Issue:4 Page(s): 228-231

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Title

CONGENITAL ANOMALIES IN INFANTS CONCEIVED BY ASSISTED REPRODUCTIVE TECHNIQUES

Author(s)

Keywords

ASSISTED REPRODUCTIVE TECHNIQUES

CONGENITAL ANOMALIES

INFANTS

INTRACYTOPLASMIC SPERM INJECTION (ICSI)

IN VITRO FERTILIZATION (IVF)

Abstract

BACKGROUND: Many studies show that congenital defects in INFANTS conceived by ASSISTED REPRODUCTIVE TECHNIQUES (ART) are more than INFANTS of normal conception (NC). The aim of this study is to determine the frequency of CONGENITAL ANOMALIES in ART INFANTS from Royan Institute and to compare CONGENITAL ANOMALIES between two ART techniques.METHODS: In a cross-sectional descriptive study, 400 ART INFANTS from Royan Institute who resided in Tehran were selected by non-random, consecutive sampling. INFANTS were examined twice (until 9 months of age) by a pediatrician. INFANTS’ CONGENITAL ANOMALIES were described by each body system or organ and type of ART. Data were analyzed by SPSS version 16 and Fisher's exact test.RESULTS: The frequency of different organ involvement in the two examinations were: 40 (10%) skin, 25 (6.2%) urogenital system, 21 (5.2%) gastrointestinal tract, 13 (3.2%) visual, and 8 (2%) cardiovascular system. Major congenital defects in INFANTS conceived by in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) were hypospadiasis, inguinal hernia, patent ductus arteriosus plus ventricular septal defect (PDA + VSD), developmental dysplasia of the hip, lacrimal duct stenosis during the first year of life, hydronephrosis and urinary reflux over grade III, undescending testis, ureteropelvic junction stenosis, and torticoli.CONCLUSIONS: Two-thirds of ART INFANTS had no defects. A total of 7% of IVF and ICSI INFANTS had one of the major abovementioned CONGENITAL ANOMALIES. This rate was higher than NC INFANTS (2%–3%). There was no difference between the ICSI and IVF group.

Cites

COMPARISON OF CONGENITAL ABNORMALITIES OF INFANTS CONCEIVED BY ASSISTED REPRODUCTIVE TECHNIQUES VERSUS INFANTS WITH NATURAL CONCEPTION IN TEHRAN

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APA: Copy

MOZAFARI KERMANI, RAMIN, NEDAEIFARD, LEILA, NATEGHI, MOHAMMAD REZA, SHAHZADEH FAZELI, ABOLHASSAN, AHMADI, EBRAHIM, OSIA, MOHAMMAD ALI, JAFARZADEHPOUR, EBRAHIM, & NOURI, SOUDABEH. (2012). CONGENITAL ANOMALIES IN INFANTS CONCEIVED BY ASSISTED REPRODUCTIVE TECHNIQUES. ARCHIVES OF IRANIAN MEDICINE, 15(4), 228-231. SID. https://sid.ir/paper/280825/en

Vancouver: Copy

MOZAFARI KERMANI RAMIN, NEDAEIFARD LEILA, NATEGHI MOHAMMAD REZA, SHAHZADEH FAZELI ABOLHASSAN, AHMADI EBRAHIM, OSIA MOHAMMAD ALI, JAFARZADEHPOUR EBRAHIM, NOURI SOUDABEH. CONGENITAL ANOMALIES IN INFANTS CONCEIVED BY ASSISTED REPRODUCTIVE TECHNIQUES. ARCHIVES OF IRANIAN MEDICINE[Internet]. 2012;15(4):228-231. Available from: https://sid.ir/paper/280825/en

IEEE: Copy

RAMIN MOZAFARI KERMANI, LEILA NEDAEIFARD, MOHAMMAD REZA NATEGHI, ABOLHASSAN SHAHZADEH FAZELI, EBRAHIM AHMADI, MOHAMMAD ALI OSIA, EBRAHIM JAFARZADEHPOUR, and SOUDABEH NOURI, “CONGENITAL ANOMALIES IN INFANTS CONCEIVED BY ASSISTED REPRODUCTIVE TECHNIQUES,” ARCHIVES OF IRANIAN MEDICINE, vol. 15, no. 4, pp. 228–231, 2012, [Online]. Available: https://sid.ir/paper/280825/en

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