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Information Journal Paper

Title

OPIUM AS A RISK FACTOR FOR UPPER GASTROINTESTINAL CANCERS: A POPULATION-BASED CASE-CONTROL STUDY IN IRAN

Pages

  2-6

Abstract

 BACKGROUND: Gastrointestinal cancers, including esophageal, gastric, liver and pancreatic are relatively common in IRAN. Furthermore, consumption of OPIUM and its derivatives (O&D) are considerable. This study, aimed to examine the association between consumption of O&D and the incidence of upper gastrointestinal (UGI) cancers.METHODS: In a matched CASE-control study in Kerman (located in southeast of IRAN), 142 patients with UGI cancers and 284 healthy people (matched in terms of age, sex and residence (urban/rural)) were recruited. Variables (using O&D, smoking, alcohol use and diet) were collected using a structured questionnaire. Conditional logistic regression models were used to assess the above mentioned association.RESULTS: OPIUM use was associated with an increased risk of UGI cancers with an adjusted OR 4.0 (95% CI: 2.2-7.0). A very strong dose-response relation was observed between consumption of O&D and the incidence of UGI cancers. (Three consumption levels-none, low and high, OR=18.7, 95% CI: 5.5–63.3). This dose-response relationship was also strong even in patients with gastric cancers (OR: 9.2, 95% CI: 2.5-33.7).Conclusion: The results of this study showed that OPIUM consumption can be a strong risk factor for UGI cancers in IRAN.

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    APA: Copy

    NAGHIBZADEH TAHAMI, AHMAD, KHANJANI, NARGES, YAZDI FEYZABADI, VAHID, VARZANDEH, MASOOMEH, & HAGHDOOST, ALI AKBAR. (2014). OPIUM AS A RISK FACTOR FOR UPPER GASTROINTESTINAL CANCERS: A POPULATION-BASED CASE-CONTROL STUDY IN IRAN. ARCHIVES OF IRANIAN MEDICINE, 17(1), 2-6. SID. https://sid.ir/paper/280868/en

    Vancouver: Copy

    NAGHIBZADEH TAHAMI AHMAD, KHANJANI NARGES, YAZDI FEYZABADI VAHID, VARZANDEH MASOOMEH, HAGHDOOST ALI AKBAR. OPIUM AS A RISK FACTOR FOR UPPER GASTROINTESTINAL CANCERS: A POPULATION-BASED CASE-CONTROL STUDY IN IRAN. ARCHIVES OF IRANIAN MEDICINE[Internet]. 2014;17(1):2-6. Available from: https://sid.ir/paper/280868/en

    IEEE: Copy

    AHMAD NAGHIBZADEH TAHAMI, NARGES KHANJANI, VAHID YAZDI FEYZABADI, MASOOMEH VARZANDEH, and ALI AKBAR HAGHDOOST, “OPIUM AS A RISK FACTOR FOR UPPER GASTROINTESTINAL CANCERS: A POPULATION-BASED CASE-CONTROL STUDY IN IRAN,” ARCHIVES OF IRANIAN MEDICINE, vol. 17, no. 1, pp. 2–6, 2014, [Online]. Available: https://sid.ir/paper/280868/en

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