SCREENING COLONOSCOPY IN FIRST-DEGREE RELATIVES OF PATIENTS WITH COLORECTAL CANCER

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BARZIN GILDA; OSTOVANEH MOHAMMAD REZA; TAYEBI SIROUS; VAHEDI HOMAYOUN; ANSARI REZA

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Journal: ARCHIVES OF IRANIAN MEDICINE Year:2014 | Volume:17 | Issue:2 Page(s): 115-117

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Title

SCREENING COLONOSCOPY IN FIRST-DEGREE RELATIVES OF PATIENTS WITH COLORECTAL CANCER

Author(s)

Keywords

COLON CANCER

FIRST DEGREE

SCREENING

POLYP

Abstract

BACKGROUND: Colorectal cancer (CRC), one of the most important causes of morbidity and mortality, has earned the attention of healthcare systems widely. SCREENING programs are designed to detect patients at risk as effectively as possible. One of the major CRC risk factors is having a family member with diagnosed CRC.Aim: To investigate the association between presence of POLYPs on colonoscopy and family history of CRC.DESIGN AND METHODS: This was a retrospective cohort study in which the data was collected from colonoscopy reports of patients with/without familial history of CRC in Masoud private clinic, Tehran, Iran from October 1, 2011 to October 1, 2012. The association between presence of colorectal POLYPs on colonoscopy and family history of CRC was then assessed.RESULTS: A total of 210 patients were included in the study, constituting two groups with/without familial history of CRC with a 1:1 ratio (105 subjects in each group). Compared to subjects with a negative family history of CRC, a 2.7-fold (CI 95%: 1.2-6.24) fold increase was observed in those with a positive family history to have colorectal POLYPs. In multivariate regression analysis, family history of CRC was the only independent variable associated with presence of colorectal POLYPs (odds ratio: 3.12, CI 95%:1.22-8).CONCLUSION: A positive family history of CRC is a risk factor for colorectal POLYPs.

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APA: Copy

BARZIN, GILDA, OSTOVANEH, MOHAMMAD REZA, TAYEBI, SIROUS, VAHEDI, HOMAYOUN, & ANSARI, REZA. (2014). SCREENING COLONOSCOPY IN FIRST-DEGREE RELATIVES OF PATIENTS WITH COLORECTAL CANCER. ARCHIVES OF IRANIAN MEDICINE, 17(2), 115-117. SID. https://sid.ir/paper/280876/en

Vancouver: Copy

BARZIN GILDA, OSTOVANEH MOHAMMAD REZA, TAYEBI SIROUS, VAHEDI HOMAYOUN, ANSARI REZA. SCREENING COLONOSCOPY IN FIRST-DEGREE RELATIVES OF PATIENTS WITH COLORECTAL CANCER. ARCHIVES OF IRANIAN MEDICINE[Internet]. 2014;17(2):115-117. Available from: https://sid.ir/paper/280876/en

IEEE: Copy

GILDA BARZIN, MOHAMMAD REZA OSTOVANEH, SIROUS TAYEBI, HOMAYOUN VAHEDI, and REZA ANSARI, “SCREENING COLONOSCOPY IN FIRST-DEGREE RELATIVES OF PATIENTS WITH COLORECTAL CANCER,” ARCHIVES OF IRANIAN MEDICINE, vol. 17, no. 2, pp. 115–117, 2014, [Online]. Available: https://sid.ir/paper/280876/en

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