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Information Journal Paper

Title

REFERENCE VALUES FOR SERUM CREATININE WITH JAFFE-COMPENSATED ASSAY IN ADULT IRANIAN SUBJECTS: TEHRAN LIPID AND GLUCOSE STUDY

Pages

  394-399

Abstract

 BACKGROUND: Chronic kidney disease is a worldwide public health problem and glomerular filtration rate (GFR), the best overall index of renal function, is most commonly estimated from SERUM CREATININE concentrations. The aim of this study was to determine REFERENCE VALUES for SERUM CREATININE concentrations using data from a population-based study in Iran.METHODS: SERUM CREATININE was measured using the Jaffe method in 5247 men and women, aged 20–88 years, participants of the Tehran Lipid and Glucose Study. For calculating Jaffe compensated creatinine values in 382 samples, it was measured using both the Jaffe and the enzymatic p-aminophenazone (PAP) methods. Linear regression analysis yielded a regression line equation of Jaffe-creatinine=0.863 × PAP-creatinine + 38.9 mmol/L (r=0.973, n=382, P<0.001). CLSI/IFCC guidelines (International Federation of Clinical Chemistry/ Clinical and Laboratory Standards Institute), non-parametric method was used for determining creatinine REFERENCE VALUES. RESULTS: REFERENCE VALUES for SERUM CREATININE ranged between 47–98 mmol/L (0.53–1.11 mg/dL), 37–68 mmol/L (0.42–0.77 mg/dL), and 37–78 mmol/L (0.42–0.88 mg/dL) in men, non-menopausal women, and menopausal women, respectively. Mean SERUM CREATININE concentration was significantly higher in men compared to women for both age  £ 50 years [70±11 vs. 50±10 mmol/L (0.79 ± 0.12 vs. 0.57 ± 0.11 mg/dL), P < 0.001] and age > 50 years [73±12 vs. 55±12 mmol/L (0.83 ± 0.14 vs. 0.62±0.14 mg/dL), P<0.001].CONCLUSION: REFERENCE VALUES for SERUM CREATININE using the compensated Jaffe method are presented in Iranian subjects, which may help with assessment of kidney function.

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    APA: Copy

    GHASEMI, ASGHAR, AZIMZADEH, IRAJ, ZAHEDIASL, SALEH, & AZIZI, FEREIDOUN. (2014). REFERENCE VALUES FOR SERUM CREATININE WITH JAFFE-COMPENSATED ASSAY IN ADULT IRANIAN SUBJECTS: TEHRAN LIPID AND GLUCOSE STUDY. ARCHIVES OF IRANIAN MEDICINE, 17(6), 394-399. SID. https://sid.ir/paper/280959/en

    Vancouver: Copy

    GHASEMI ASGHAR, AZIMZADEH IRAJ, ZAHEDIASL SALEH, AZIZI FEREIDOUN. REFERENCE VALUES FOR SERUM CREATININE WITH JAFFE-COMPENSATED ASSAY IN ADULT IRANIAN SUBJECTS: TEHRAN LIPID AND GLUCOSE STUDY. ARCHIVES OF IRANIAN MEDICINE[Internet]. 2014;17(6):394-399. Available from: https://sid.ir/paper/280959/en

    IEEE: Copy

    ASGHAR GHASEMI, IRAJ AZIMZADEH, SALEH ZAHEDIASL, and FEREIDOUN AZIZI, “REFERENCE VALUES FOR SERUM CREATININE WITH JAFFE-COMPENSATED ASSAY IN ADULT IRANIAN SUBJECTS: TEHRAN LIPID AND GLUCOSE STUDY,” ARCHIVES OF IRANIAN MEDICINE, vol. 17, no. 6, pp. 394–399, 2014, [Online]. Available: https://sid.ir/paper/280959/en

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