THE FREQUENCY OF HHV-8 INFECTION IN OTHERWISE HEALTHY BLOOD DONORS AS WELL AS RENAL ALLOGRAFT RECIPIENTS LIVING IN IRAN

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HOSSEINI MOGHADDAM SEYED MOHAMMADMEHDI; KEYVANI HOSSEIN; SOLEIMANIRAHBAR ATA; KARIMI GHARIB; DANESHVAR SIMIN; BASIRI ABBAS; RAZZAGHI ZAHRA; NAFAR MOHSEN; POUR REZA GHOLI FATEMEH; FARHANGI SOUDABEH

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Journal: ARCHIVES OF IRANIAN MEDICINE Year:2013 | Volume:16 | Issue:7 Page(s): 376-379

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Title

THE FREQUENCY OF HHV-8 INFECTION IN OTHERWISE HEALTHY BLOOD DONORS AS WELL AS RENAL ALLOGRAFT RECIPIENTS LIVING IN IRAN

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HUMAN HERPESVIRUS 8

KIDNEY TRANSPLANTATION

Abstract

BACKGROUND: Different reports from Middle East countries demonstrated Kaposi’s sarcoma (KS) in transplant population. This vascular malignancy occurs mostly among immunocompromised individuals. HUMAN HERPESVIRUS 8 (HHV-8) appears to be the causative factor for the development of this neoplasm. Transplant programs are concerned about the frequencies of HHV-8 infection either in general population or transplant patients.METHODS: The current study was conducted in two phases. Firstly, we detected antibodies against HHV-8 in 790 otherwise healthy blood donors. Secondly, a total of 125 kidney allograft recipients evaluated as being seropositive for HHV-8. We utilized enzyme immunoassay (EIA) for serologic studies.RESULTS: Among blood donors, the male to female ratio was 1.05 (405 vs. 385) while the mean age was 38.9±11.7 years. The serostatus of none of these blood donors were positive for HHV-8. Among kidney recipients, the male to female ratio was 1.9 (82 vs. 43). The mean age was 39.01±14.77 years. Two (1.6%) patients were seropositive for HHV-8.CONCLUSION: The prevalence of HHV-8 infection among Iranians is likely to be low. Yet, owing to the evidence of this infection among kidney allograft recipients and its probable role in developing post- transplantation KS (PT-KS), further studies appear to be required to keep the various aspects of this infection under close surveillance.

Cites

MOLECULAR EPIDEMIOLOGY OF KAPOSI’S SARCOMA-ASSOCIATED HERPES VIRUS, AND RISK FACTORS IN HIV-INFECTED PATIENTS IN TEHRAN, 2014

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APA: Copy

HOSSEINI MOGHADDAM, SEYED MOHAMMADMEHDI, KEYVANI, HOSSEIN, SOLEIMANIRAHBAR, ATA, KARIMI, GHARIB, DANESHVAR, SIMIN, BASIRI, ABBAS, RAZZAGHI, ZAHRA, NAFAR, MOHSEN, POUR REZA GHOLI, FATEMEH, & FARHANGI, SOUDABEH. (2013). THE FREQUENCY OF HHV-8 INFECTION IN OTHERWISE HEALTHY BLOOD DONORS AS WELL AS RENAL ALLOGRAFT RECIPIENTS LIVING IN IRAN. ARCHIVES OF IRANIAN MEDICINE, 16(7), 376-379. SID. https://sid.ir/paper/281068/en

Vancouver: Copy

HOSSEINI MOGHADDAM SEYED MOHAMMADMEHDI, KEYVANI HOSSEIN, SOLEIMANIRAHBAR ATA, KARIMI GHARIB, DANESHVAR SIMIN, BASIRI ABBAS, RAZZAGHI ZAHRA, NAFAR MOHSEN, POUR REZA GHOLI FATEMEH, FARHANGI SOUDABEH. THE FREQUENCY OF HHV-8 INFECTION IN OTHERWISE HEALTHY BLOOD DONORS AS WELL AS RENAL ALLOGRAFT RECIPIENTS LIVING IN IRAN. ARCHIVES OF IRANIAN MEDICINE[Internet]. 2013;16(7):376-379. Available from: https://sid.ir/paper/281068/en

IEEE: Copy

SEYED MOHAMMADMEHDI HOSSEINI MOGHADDAM, HOSSEIN KEYVANI, ATA SOLEIMANIRAHBAR, GHARIB KARIMI, SIMIN DANESHVAR, ABBAS BASIRI, ZAHRA RAZZAGHI, MOHSEN NAFAR, FATEMEH POUR REZA GHOLI, and SOUDABEH FARHANGI, “THE FREQUENCY OF HHV-8 INFECTION IN OTHERWISE HEALTHY BLOOD DONORS AS WELL AS RENAL ALLOGRAFT RECIPIENTS LIVING IN IRAN,” ARCHIVES OF IRANIAN MEDICINE, vol. 16, no. 7, pp. 376–379, 2013, [Online]. Available: https://sid.ir/paper/281068/en

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