CASE REPORT, DATSCAN IN DIFFERENTIAL DIAGNOSTICS OF LEWY BODY DISEASE

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LUZNY JAN; IVANOVA KATERINA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: ARCHIVES OF IRANIAN MEDICINE Year:2016 | Volume:19 | Issue:6 Page(s): 449-452

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Information Journal Paper

Title

CASE REPORT, DATSCAN IN DIFFERENTIAL DIAGNOSTICS OF LEWY BODY DISEASE

Author(s)

LUZNY JAN | IVANOVA KATERINA | Issue Writer Certificate

Keywords

ALZHEIMER'S DISEASE

DATSCAN

DIFFERENTIAL DIAGNOSIS

LEWY BODY DISEASE

SPECT

Abstract

Differential diagnosis between LEWY BODY DISEASE and Alzheimer’s disease might be difficult because of similarities of clinical symptoms in both neurodegenerative diseases. DATSCAN is a modern functional neuroimmaging method which differentiates between this similar diseases and helps in correct treatment strategy. We report our positive experience with DATSCAN in differentiating LEWY BODY DISEASE from Alzheimer´s disease. This is a case report of a woman with LEWY BODY DISEASE, initially diagnosed as Alzheimer’s disease. DATSCAN neuroimmaging method was used in DIFFERENTIAL DIAGNOSIS of dementia. Memory impairment, impaired activities of daily living, sleep and behavioral disturbances were present in our case. Donepezil was well tolerated, but haloperidol administration was followed by development of severe dystonia. DATSCAN showed deficient dopaminergic presynaptic transport in substantia nigra and striatum. This finding is typical for LEWY BODY DISEASE not for Alzheimer’s disease. DATSCAN neuroimmaging is a suitable method for differentiating LEWY BODY DISEASE from Alzheimer´s disease. Deficient dopaminergic presynaptic transport in substantia nigra and striatum is typical for LEWY BODY DISEASE.

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APA: Copy

LUZNY, JAN, & IVANOVA, KATERINA. (2016). CASE REPORT, DATSCAN IN DIFFERENTIAL DIAGNOSTICS OF LEWY BODY DISEASE. ARCHIVES OF IRANIAN MEDICINE, 19(6), 449-452. SID. https://sid.ir/paper/281372/en

Vancouver: Copy

LUZNY JAN, IVANOVA KATERINA. CASE REPORT, DATSCAN IN DIFFERENTIAL DIAGNOSTICS OF LEWY BODY DISEASE. ARCHIVES OF IRANIAN MEDICINE[Internet]. 2016;19(6):449-452. Available from: https://sid.ir/paper/281372/en

IEEE: Copy

JAN LUZNY, and KATERINA IVANOVA, “CASE REPORT, DATSCAN IN DIFFERENTIAL DIAGNOSTICS OF LEWY BODY DISEASE,” ARCHIVES OF IRANIAN MEDICINE, vol. 19, no. 6, pp. 449–452, 2016, [Online]. Available: https://sid.ir/paper/281372/en

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