OUTER DENSE FIBER PROTEINS: BRIDGING BETWEEN MALEINFERTILITY AND CANCER

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AZIZI FAEZEH; GHAFOURI FARD SOUDEH

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Journal Paper

Paper Information

Journal: ARCHIVES OF IRANIAN MEDICINE Year:2017 | Volume:20 | Issue:5 Page(s): 320-325

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Title

OUTER DENSE FIBER PROTEINS: BRIDGING BETWEEN MALEINFERTILITY AND CANCER

Author(s)

AZIZI FAEZEH | GHAFOURI FARD SOUDEH | Issue Writer Certificate

Keywords

CANCER

GAMETOGENESIS

INFERTILITY

OUTER DENSE FIBER PROTEINS

Abstract

BACKGROUND: The similarities between gametogenic and carcinogenesis processes have been noted for more than decades. Among prominent similarities between these two processes is expression of a group of antigens, namely CANCER-testis antigens in both the testes and various CANCER tissues. Outer dense fiber (ODF) proteins are testis-specific proteins localized to sperm tails and involved in sperm motility. METHODS: We performed a computerized search of the MEDLINE/PUBMED databases with keywords "outer dense fiber, ODF, CANCER, testis, GAMETOGENESIS and INFERTILITY". RESULTS: The results of animal and human studies show ODF contribution to male fertility. In addition, ODFs are expressed in some CANCERs, including prostate adenocarcinoma, breast CANCER, chronic myeloid leukemia and basal cell carcinoma. CONCLUSION: ODF expression analysis in CANCER may pave the way for identification of CANCER biomarkers or therapeutic targets.

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APA: Copy

AZIZI, FAEZEH, & GHAFOURI FARD, SOUDEH. (2017). OUTER DENSE FIBER PROTEINS: BRIDGING BETWEEN MALEINFERTILITY AND CANCER. ARCHIVES OF IRANIAN MEDICINE, 20(5), 320-325. SID. https://sid.ir/paper/281642/en

Vancouver: Copy

AZIZI FAEZEH, GHAFOURI FARD SOUDEH. OUTER DENSE FIBER PROTEINS: BRIDGING BETWEEN MALEINFERTILITY AND CANCER. ARCHIVES OF IRANIAN MEDICINE[Internet]. 2017;20(5):320-325. Available from: https://sid.ir/paper/281642/en

IEEE: Copy

FAEZEH AZIZI, and SOUDEH GHAFOURI FARD, “OUTER DENSE FIBER PROTEINS: BRIDGING BETWEEN MALEINFERTILITY AND CANCER,” ARCHIVES OF IRANIAN MEDICINE, vol. 20, no. 5, pp. 320–325, 2017, [Online]. Available: https://sid.ir/paper/281642/en

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