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Information Journal Paper

Title

Clinical Spectrum of Celiac Disease in Children in Sistan and Baluchestan Province

Pages

  762-766

Abstract

 Background: The clinical manifestations of Celiac disease (CD) have changed in the past decades. There are currently little data describing the initial clinical manifestations of CD in children in Iran. This study describes the initial presentation of children with suspected 􀀦 􀀧 􀀃 􀁉 􀁕 􀁒 􀁐 􀀃 􀁄 􀀃 􀁊 􀁈 􀁒 􀁊 􀁕 􀁄 􀁓 􀁋 􀁌 􀁆 􀁄 􀁏 􀁏 􀁜 􀀃 􀁇 􀁈 􀂿 􀁑 􀁈 􀁇 􀀃 􀁕 􀁈 􀁊 􀁌 􀁒 􀁑 􀀃 􀁌 􀁑 􀀃 􀀬 􀁕 􀁄 􀁑 􀀑 Method: Medical records of children seen in 2007 – 2015 from Sistan and Baluchestan province, Iran, with suspected CD were reviewed. After obtaining TTG-IgA and IgA, subjects were divided into three groups according to presenting symptoms: GI, non-GI, and asymptomatic group. Those with elevated TTG-IgA or a strong clinical suspicion for CD underwent endoscopy with duodenal biopsy. Demographic data, 􀁖 􀁜 􀁐 􀁓 􀁗 􀁒 􀁐 􀁖 􀀏 􀀃 􀁏 􀁄 􀁅 􀁒 􀁕 􀁄 􀁗 􀁒 􀁕 􀁜 􀀏 􀀃 􀁋 􀁌 􀁖 􀁗 􀁒 􀁓 􀁄 􀁗 􀁋 􀁒 􀁏 􀁒 􀁊 􀁜 􀀃 􀂿 􀁑 􀁇 􀁌 􀁑 􀁊 􀁖 􀀃 􀁄 􀁑 􀁇 􀀃 􀁗 􀁋 􀁈 􀀃 􀁓 􀁕 􀁈 􀁖 􀁈 􀁑 􀁆 􀁈 􀀃 􀁒 􀁉 􀀃 􀁄 􀁑 􀁜 􀀃 􀀦 􀀧 􀀃 􀁕 􀁈 􀁏 􀁄 􀁗 􀁈 􀁇 􀀃 􀁆 􀁒 􀁑 􀁇 􀁌 􀁗 􀁌 􀁒 􀁑 􀁖 􀀃 􀁚 􀁈 􀁕 􀁈 􀀃 􀁕 􀁈 􀁆 􀁒 􀁕 􀁇 􀁈 􀁇 􀀑 􀀃 Results: from 344 children who underwent upper endoscopy and intestinal biopsy, 105 cases with marsh 0 – 1 were excluded from the 􀁖 􀁗 􀁘 􀁇 􀁜 􀀃 􀁄 􀁑 􀁇 􀀃 􀀕 􀀖 􀀜 􀀃 􀁆 􀁄 􀁖 􀁈 􀁖 􀀃 􀁆 􀁒 􀁑 􀁖 􀁌 􀁇 􀁈 􀁕 􀁈 􀁇 􀀃 􀁄 􀁖 􀀃 􀁄 􀀃 􀁇 􀁈 􀂿 􀁑 􀁌 􀁗 􀁈 􀀃 􀁆 􀁈 􀁏 􀁌 􀁄 􀁆 􀀃 􀁇 􀁌 􀁖 􀁈 􀁄 􀁖 􀁈 􀀃 􀀋 􀀰 􀁈 􀁄 􀁑 􀂓 􀀃 􀀶 􀀧 􀀃 􀁒 􀁉 􀀃 􀁄 􀁊 􀁈 􀀃 􀁚 􀁄 􀁖 􀀃 􀀙 􀀑 􀀛 􀀃 􀂓 􀀃 􀀖 􀀑 􀀜 􀀃 􀁜 􀁈 􀁄 􀁕 􀁖 􀀃 􀁚 􀁌 􀁗 􀁋 􀀃 􀀔 􀀗 􀀘 􀀃 􀁉 􀁈 􀁐 􀁄 􀁏 􀁈 􀁖 􀀌 􀀑 􀀃 􀀪 􀀬 􀀃 􀁖 􀁜 􀁐 􀁓 􀁗 􀁒 􀁐 􀁖 􀀃 􀁚 􀁈 􀁕 􀁈 􀀃 predominant in the younger age groups while non-GI symptoms were more common in the older children. The most frequent GI and Non-GI symptoms were abdominal pain (41. 4%), distension (36. 4%), diarrhea (32. 2%), under nutrition (51. 4%), anemia (36. 4%), and decreased bone age (35%). The most common co-morbidities were hypothyroidism (3. 7%) and Type 1 diabetes (2. 9%). Conclusion: GI complaints in Iranian children are a common feature. Screening of children with suspected CD, especially with GI symptom is highly recommended.

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    • Cite

    APA: Copy

    SHAHRAKI, TOURAN, & Hill, Ivor D.. (2016). Clinical Spectrum of Celiac Disease in Children in Sistan and Baluchestan Province. ARCHIVES OF IRANIAN MEDICINE, 19(11), 762-766. SID. https://sid.ir/paper/281744/en

    Vancouver: Copy

    SHAHRAKI TOURAN, Hill Ivor D.. Clinical Spectrum of Celiac Disease in Children in Sistan and Baluchestan Province. ARCHIVES OF IRANIAN MEDICINE[Internet]. 2016;19(11):762-766. Available from: https://sid.ir/paper/281744/en

    IEEE: Copy

    TOURAN SHAHRAKI, and Ivor D. Hill, “Clinical Spectrum of Celiac Disease in Children in Sistan and Baluchestan Province,” ARCHIVES OF IRANIAN MEDICINE, vol. 19, no. 11, pp. 762–766, 2016, [Online]. Available: https://sid.ir/paper/281744/en

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