HOW TO USE MR-CONTRAST AGENT IN TUMOR INDUCED EPILEPSIS

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JALAL SHOKOUHI J.; NOROUZI A.; MOHAMMADPOUR H.; AMERI ALI AKBAR; SHIRAZI M.

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Journal: IRANIAN JOURNAL OF RADIOLOGY Year:2010 | Volume:7 | Issue:SUPPLEMENT 1 (26TH IRANIAN CONGRESS OF RADIOLOGY) Page(s): 0-0

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Title

HOW TO USE MR-CONTRAST AGENT IN TUMOR INDUCED EPILEPSIS

Author(s)

JALAL SHOKOUHI J. | NOROUZI A. | MOHAMMADPOUR H. | AMERI ALI AKBAR | SHIRAZI M.

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Abstract

By year of 1990, second MRI revolution has hap-pened in the diagnosis of infection and tumor assessment "first revolution was made by clinical MRI invention in the early 1980's".Tumor-associated epilepsis is an important contributor to morbidity in patients with brain tumors. Perilesional tissue changes play a vital role in the generation of tumor-associated seizures.Tumor-associated seizure is usually focal with secondary generalization and often resistant to antiepileptic drugs.For studying the tumor well and diagnosis, contrast injection is a necessity and T1 pulse is used for demonstration. It needs pre-contrast T1 to compare with post contrast T1. Contrast agent "Gadolinium" changes the relaxation time of tissue in T1 pulse "shortening the time". Contrast circulation in the body is in a close circuit from vein or artery to the capillary system, interstitial tissue and contrast does not go inside the normal cells except in hepatocytes, pituicytes and damaged cells "broken blood brain barrier".For tumor diagnosis, MRI with and without Gadolinium is used more than x-ray CT techniques.Other diagnostic techniques for tumor D.D.X and epilepsis are PET, SPECT, EEG, MEG "MSI" and ultrasound. Tested Double Dose contrasted images "2 x 1mmol/kg" of Gadolinium by 1.5 Tesla machine increased the enhancement rate about 5-10% but needs double money for contrast. Using 3 Tesla machine also increases signal demonstration but today all imaging "95%" is sufficient by 1.5 Tesla and imaging by 3-Tesla is difficult and expensive. Conclusion: 1/ Please request MRI with and without GD for tumor diagnosis "pre-contrast T1and post contrast T1 is necessary to diagnosis and D.D.X of any hemorrhage inside the tumor versus enhancement". 2/ Please do not request double dose contrast for imaging "it is more expensive and less effective". 3/ Please request your patients imaging by 1.5 Tesla "3 Tesla imaging is difficult and more expensive". 4/Requesting only contrasted MRI is not exact and less scientific, for tumor diagnosis "Radiologist needs pre-contrast T1 and post contrast T1 to compare".

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APA: Copy

JALAL SHOKOUHI, J., NOROUZI, A., MOHAMMADPOUR, H., AMERI, ALI AKBAR, & SHIRAZI, M.. (2010). HOW TO USE MR-CONTRAST AGENT IN TUMOR INDUCED EPILEPSIS. IRANIAN JOURNAL OF RADIOLOGY, 7(SUPPLEMENT 1 (26TH IRANIAN CONGRESS OF RADIOLOGY)), 0-0. SID. https://sid.ir/paper/284022/en

Vancouver: Copy

JALAL SHOKOUHI J., NOROUZI A., MOHAMMADPOUR H., AMERI ALI AKBAR, SHIRAZI M.. HOW TO USE MR-CONTRAST AGENT IN TUMOR INDUCED EPILEPSIS. IRANIAN JOURNAL OF RADIOLOGY[Internet]. 2010;7(SUPPLEMENT 1 (26TH IRANIAN CONGRESS OF RADIOLOGY)):0-0. Available from: https://sid.ir/paper/284022/en

IEEE: Copy

J. JALAL SHOKOUHI, A. NOROUZI, H. MOHAMMADPOUR, ALI AKBAR AMERI, and M. SHIRAZI, “HOW TO USE MR-CONTRAST AGENT IN TUMOR INDUCED EPILEPSIS,” IRANIAN JOURNAL OF RADIOLOGY, vol. 7, no. SUPPLEMENT 1 (26TH IRANIAN CONGRESS OF RADIOLOGY), pp. 0–0, 2010, [Online]. Available: https://sid.ir/paper/284022/en

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