Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

38
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

10
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

RADIATION-INDUCED ACUTE KIDNEY TOXICITY: PROTECTIVE EFFECT OF L-CARNITINE VERSUS AMIFOSTINE

Pages

  317-324

Abstract

 Background: The aim of the study was to compare the radioprotective efficacy in the KIDNEY of L-CARNITINE to that of amifostine.Materials and Methods: Thirty three-month-old Wistar albino rats were randomly assigned to four groups: Group 1 (Control); Group 2 (Irradiation alone); Group 3 (amifostine plus irradiation); and Group 4 (L-carnitine before irradiation). The rats in Groups 2, 3, and 4 were irradiated individually with a single dose of 20 Gy to whole abdomen. L-CARNITINE (300 mg/kg) or amifostine (200 mg/kg) was administered 30 minutes before irradiation. Euthanasia was performed 5 days a/er irradiation, and KIDNEYs were evaluated histopathologically.Results: Dilatation of Bowman’s capsule, congeson of blood vessels, and tubular epithelial degeneraon were significantly different among the groups (p<0.05). Pretreatment with both L-CARNITINE and amifostine reduced the radiation-induced dilatation of Bowman’s capsule (p<0.05), congeson of blood vessels (p<0.05), and tubular epithelial degeneration (p<0.05).L-carnitine and amifostine were similar in protective effect.Conclusion: L-CARNITINE was equally effective as amifostine in protecting the KIDNEY against acute irradiation damage.

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    YURUT CALOGLU, V., CALOGLU, M., DENIZ YALTA, T., AKTOZ, T., KILIC DURANKUS, N., ARDA, E., TURKKAN, G., & INCI, O.. (). . , (), -. SID. https://sid.ir/paper/286684/en

    Vancouver: Copy

    YURUT CALOGLU V., CALOGLU M., DENIZ YALTA T., AKTOZ T., KILIC DURANKUS N., ARDA E., TURKKAN G., INCI O.. . [Internet]. ;():-. Available from: https://sid.ir/paper/286684/en

    IEEE: Copy

    V. YURUT CALOGLU, M. CALOGLU, T. DENIZ YALTA, T. AKTOZ, N. KILIC DURANKUS, E. ARDA, G. TURKKAN, and O. INCI, “,” , vol. , no. , pp. –, , [Online]. Available: https://sid.ir/paper/286684/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top