Accuracy of the dose delivery in prostate cancer patients-using an electronic portal imaging device (EPID)

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MAHDAVI S.R.; JAZAYERI GHAREHBAGH E.; MOFID B.; JAFARI A.H.; NIKOOFAR A.R.

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Journal: International Journal of Radiation Research Year:2017 | Volume:15 | Issue:1 Page(s): 39-47

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Title

Accuracy of the dose delivery in prostate cancer patients-using an electronic portal imaging device (EPID)

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Abstract

Background: To correct pa ent posi oning errors (setup errors) during prostate cancer treatment using EPID and fiducial gold markers, to improve the accuracy of the dose delivery in these pa ents. Materials and Methods: Fi"een pa ents with localized prostate carcinoma a"er implanta on of fiducial gold markers in their prostate gland underwent the five-field IMRT planning technique. The plan was prepared in accordance with ICRU 50 guidance (PTV to receive 95-107% dose). The so"ware program reconstructed the three-dimensional posi on of the markers from the different Beams Eye Views (BEV). The discrepancies of the seeds’ posi ons (prostate surrogate) between plan and daily images were calculated three dimensionally. Then, necessary correc ons were applied to match the prostate fiducial markers in the portal image with the BEV image in the planned one by moving the couch in the X, Y and Z direc ons. Results: Data from 15 pa ents and 469 frac ons of radiotherapy were analyzed in this study. Two sets of data were available from EPID so"ware before and a"er 3D set-up correc ons. The mean of the popula on displacement in Le" /Right (L/R), Anterior/Posterior (A/P) and Crania/Caudal (C/C) direc ons were 0. 5,-1. 0 and 2. 4mm before, and-0. 1,-0. 5 and 0. 9mm a"er correc ons, respec vely. The systema c and random errors for the measured popula ons in the three men oned direc ons were 2. 4, 2. 7 and 2mm and 6. 4, 5. 9 and 6. 1mm before correc ons, and 1. 1, 2. 4 and 1. 4mm and 3. 8, 3. 9 and 3. 6mm a"er correc ons, correspondingly. Conclusion: This study provides further evidence that using gold markers in the prostate improves dose delivery to the prostate. Also, it has been demonstrated that the EPID can be a powerful tool in the reduc on of treatment setup errors and the quality assurance and verifica on of complex treatments.

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Methods to evaluate the performance of kilovoltage cone-beam computed tomography in the threedimensional reconstruction space

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APA: Copy

MAHDAVI, S.R., JAZAYERI GHAREHBAGH, E., MOFID, B., JAFARI, A.H., & NIKOOFAR, A.R.. (2017). Accuracy of the dose delivery in prostate cancer patients-using an electronic portal imaging device (EPID). INTERNATIONAL JOURNAL OF RADIATION RESEARCH, 15(1), 39-47. SID. https://sid.ir/paper/286777/en

Vancouver: Copy

MAHDAVI S.R., JAZAYERI GHAREHBAGH E., MOFID B., JAFARI A.H., NIKOOFAR A.R.. Accuracy of the dose delivery in prostate cancer patients-using an electronic portal imaging device (EPID). INTERNATIONAL JOURNAL OF RADIATION RESEARCH[Internet]. 2017;15(1):39-47. Available from: https://sid.ir/paper/286777/en

IEEE: Copy

S.R. MAHDAVI, E. JAZAYERI GHAREHBAGH, B. MOFID, A.H. JAFARI, and A.R. NIKOOFAR, “Accuracy of the dose delivery in prostate cancer patients-using an electronic portal imaging device (EPID),” INTERNATIONAL JOURNAL OF RADIATION RESEARCH, vol. 15, no. 1, pp. 39–47, 2017, [Online]. Available: https://sid.ir/paper/286777/en

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