GELATIN MICROSPHERES FOR THE CONTROLLED RELEASE OF ALL-TRANS-RETINOIC ACID TOPICAL FORMULATION AND DRUG DELIVERY EVALUATION

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DINARVAND R.; RAHMANI ELHAM; FARBOD E.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Pharmaceutical Research Year:2003 | Volume:2 | Issue:1 Page(s): 47-50

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Information Journal Paper

Title

GELATIN MICROSPHERES FOR THE CONTROLLED RELEASE OF ALL-TRANS-RETINOIC ACID TOPICAL FORMULATION AND DRUG DELIVERY EVALUATION

Author(s)

DINARVAND R. | RAHMANI ELHAM | FARBOD E. | Issue Writer Certificate

Keywords

ALL-TRANS-RETINOIC ACID

TRETINOIN

MICROENCAPSULATION

GELATIN MICROSPHERES

COACERVATION

ZERO ORDER RELEASE

TOPICAL CREAM

Abstract

A topical o/w cream containing TRETINOIN microspheres was prepared. GELATIN MICROSPHERES of TRETINOIN were prepared using COACERVATION method. These microspheres contained about 50% w/w TRETINOIN. The particle size range of microspheres was between 90-150mm. In vitro drug release from microspheres and a cream formulation was studied. It was shown that drug release from microspheres followed Higuchi kinetics of release. However, drug release from the cream formulation followed ZERO ORDER RELEASE profile.

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APA: Copy

DINARVAND, R., RAHMANI, ELHAM, & FARBOD, E.. (2003). GELATIN MICROSPHERES FOR THE CONTROLLED RELEASE OF ALL-TRANS-RETINOIC ACID TOPICAL FORMULATION AND DRUG DELIVERY EVALUATION. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 2(1), 47-50. SID. https://sid.ir/paper/286941/en

Vancouver: Copy

DINARVAND R., RAHMANI ELHAM, FARBOD E.. GELATIN MICROSPHERES FOR THE CONTROLLED RELEASE OF ALL-TRANS-RETINOIC ACID TOPICAL FORMULATION AND DRUG DELIVERY EVALUATION. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2003;2(1):47-50. Available from: https://sid.ir/paper/286941/en

IEEE: Copy

R. DINARVAND, ELHAM RAHMANI, and E. FARBOD, “GELATIN MICROSPHERES FOR THE CONTROLLED RELEASE OF ALL-TRANS-RETINOIC ACID TOPICAL FORMULATION AND DRUG DELIVERY EVALUATION,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 2, no. 1, pp. 47–50, 2003, [Online]. Available: https://sid.ir/paper/286941/en

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