SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME NEW ISATIN DERIVATIVES

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PATEL A.; BARI S.; TALELE G.; PATEL J.; SARANGAPANI M.

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Paper Information

Journal: IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH Year:2006 | Volume:5 | Issue:4 Page(s): 249-254

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Title

SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME NEW ISATIN DERIVATIVES

Author(s)

Keywords

ISATIN

ISATIN HYDRAZONE

IMIDAZOLONE

ANTIBACTERIAL

ANTIFUNGAL

Abstract

Some new 3-[(5-benzylidene-2-phenyl)-3, 5-dihydro-4-H-imidazol-4-one-3-(4-bezoylhydrazono)]-indole-2-ones (VIII) have been synthesized from different isatinhydrazones (II) by condensing with 2-phenyl-5-benzylidene-3-N (4-acetyl phenyl)-1, 5-dihydro-imidazol-4-one (VII). Their chemical structures have been confirmed by IR, 1HNMR, MASS and by elemental analysis. Investigation of antimicrobial activity of compounds was done by the disk diffusion technique. Among the compounds tested, the compound with 5-Br substitution showed the most favourable antimicrobial activity.

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APA: Copy

PATEL, A., BARI, S., TALELE, G., PATEL, J., & SARANGAPANI, M.. (2006). SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME NEW ISATIN DERIVATIVES. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 5(4), 249-254. SID. https://sid.ir/paper/287606/en

Vancouver: Copy

PATEL A., BARI S., TALELE G., PATEL J., SARANGAPANI M.. SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME NEW ISATIN DERIVATIVES. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2006;5(4):249-254. Available from: https://sid.ir/paper/287606/en

IEEE: Copy

A. PATEL, S. BARI, G. TALELE, J. PATEL, and M. SARANGAPANI, “SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME NEW ISATIN DERIVATIVES,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 5, no. 4, pp. 249–254, 2006, [Online]. Available: https://sid.ir/paper/287606/en

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