EFFECTS OF LYCOPENE ON THE SUSCEPTIBILITY OF LOW-DENSITY LIPOPROTEINS TO OXIDATIVE MODIFICATION

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SAFARI M.R.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Pharmaceutical Research Year:2007 | Volume:6 | Issue:3 Page(s): 173-177

Download Full-Text

View:

288

Download:

170

Cites:

Information Journal Paper

Title

EFFECTS OF LYCOPENE ON THE SUSCEPTIBILITY OF LOW-DENSITY LIPOPROTEINS TO OXIDATIVE MODIFICATION

Author(s)

SAFARI M.R. | Issue Writer Certificate

Keywords

ATHEROSCLEROSIS

LOW-DENSITY LIPOPROTEIN

LYCOPENE

OXIDATION

Abstract

The intake of antioxidants intake has been reported to be inversely associated with the incidence of coronary artery disease. To clarify the possible role of lipophilic antioxidants in prevention of ATHEROSCLEROSIS, we investigated the effects of LYCOPENE on the susceptibility of LOW-DENSITY LIPOPROTEIN (LDL) to oxidative modification. In this study, "lycopene" was added to plasma and incubated for 3 h at 37°C. Then, the LDL fraction was separated by ultracentrifugation. The oxidizability of LDL was estimated by measuring conjugated dienes (CD), lipid peroxides and thiobarbituric acid-reactive substances (TBARS) after addition of cupric sulfate solution.Weshowedthat LYCOPENE significantly (P<0.01 by ANOVA) and dose-dependentlyprolonged the lag time before the initiation of OXIDATION reaction. Also, it suppressed the formation of lipid peroxides and TBARS more markedly than the control. LDL exposed to LYCOPENE in vitro reduced oxidizability. These findings raise the possibility that LYCOPENE has a role in ameliorating ATHEROSCLEROSIS.

Cites

No record.

References

No record.

Cite

APA: Copy

SAFARI, M.R.. (2007). EFFECTS OF LYCOPENE ON THE SUSCEPTIBILITY OF LOW-DENSITY LIPOPROTEINS TO OXIDATIVE MODIFICATION. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 6(3), 173-177. SID. https://sid.ir/paper/287643/en

Vancouver: Copy

SAFARI M.R.. EFFECTS OF LYCOPENE ON THE SUSCEPTIBILITY OF LOW-DENSITY LIPOPROTEINS TO OXIDATIVE MODIFICATION. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2007;6(3):173-177. Available from: https://sid.ir/paper/287643/en

IEEE: Copy

M.R. SAFARI, “EFFECTS OF LYCOPENE ON THE SUSCEPTIBILITY OF LOW-DENSITY LIPOPROTEINS TO OXIDATIVE MODIFICATION,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 6, no. 3, pp. 173–177, 2007, [Online]. Available: https://sid.ir/paper/287643/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops