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Information Journal Paper

Title

ANTIOXIDANT, ANTIMICROBIAL AND PHYTOCHEMICAL ANALYSIS OF CICHORIUMINTYBUS SEEDS EXTRACT AND VARIOUS ORGANIC FRACTIONS

Pages

  1145-1151

Abstract

 This study was carried out to evaluate the antimicrobial and antioxidant effectiveness of methanolic extract and different fractions (n-butanol, ethyl acetate, chloroform and n-hexane) of C. INTYBUS seeds. The ANTIMICROBIAL ACTIVITY was determined by the disc diffusion method and MINIMUM INHIBITORY CONCENTRATION (MIC) against a panel of microorganisms (four bacterial strains, i.e. P. multocida, E. coli, B. subtilis and S. aureus and three fungal strains, i.e A. FLAVUS, A. niger and R. solani). The results indicated that seeds extract and fractions of C. INTYBUS showed moderate activity as antibacterial agent. While Antifungal activity of C. INTYBUS seeds extract/fractions was very low against A. FLAVUS and A. niger while mild against R. solani. The C. INTYBUS seeds extract/fractions contained appreciable levels of total phenolic contents (50.8-285 GAE mg/100 g of Dry plant matter) and total flavonoid contents (43.3-150 CE mg/100 g of Dry plant matter). The C. INTYBUS seed extract/fractions also exhibited good DPPH radical scavenging activity, with IC50 ranging from 21.28-72.14 mg/mL. Of the C. INTYBUS seeds solvent extract/fractions tested, 100% methanolic extract and ethylacetate fraction exhibited the maximum antioxidant activity. The results of the present investigation demonstrated significant (p<0.01) variations in the antioxidant and antimicrobial activities of C. INTYBUS seeds solvent extract/fractions.

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    APA: Copy

    MEHMOOD, NASIR, ZUBAIR, MUHAMMAD, RIZWAN, KOMAL, RASOOL, NASIR, SHAHID, MUHAMMAD, & AHMAD, VIQAR UDDIN. (2012). ANTIOXIDANT, ANTIMICROBIAL AND PHYTOCHEMICAL ANALYSIS OF CICHORIUMINTYBUS SEEDS EXTRACT AND VARIOUS ORGANIC FRACTIONS. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 11(4), 1145-1151. SID. https://sid.ir/paper/288017/en

    Vancouver: Copy

    MEHMOOD NASIR, ZUBAIR MUHAMMAD, RIZWAN KOMAL, RASOOL NASIR, SHAHID MUHAMMAD, AHMAD VIQAR UDDIN. ANTIOXIDANT, ANTIMICROBIAL AND PHYTOCHEMICAL ANALYSIS OF CICHORIUMINTYBUS SEEDS EXTRACT AND VARIOUS ORGANIC FRACTIONS. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2012;11(4):1145-1151. Available from: https://sid.ir/paper/288017/en

    IEEE: Copy

    NASIR MEHMOOD, MUHAMMAD ZUBAIR, KOMAL RIZWAN, NASIR RASOOL, MUHAMMAD SHAHID, and VIQAR UDDIN AHMAD, “ANTIOXIDANT, ANTIMICROBIAL AND PHYTOCHEMICAL ANALYSIS OF CICHORIUMINTYBUS SEEDS EXTRACT AND VARIOUS ORGANIC FRACTIONS,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 11, no. 4, pp. 1145–1151, 2012, [Online]. Available: https://sid.ir/paper/288017/en

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