COMPUTATIONAL AIDED-MOLECULAR IMPRINTED POLYMER DESIGN FOR SOLID PHASE EXTRACTION OF METAPROTERENOL FROM PLASMA AND DETERMINATION BY VOLTAMMETRY USING MODIFIED CARBON NANOTUBE ELECTRODE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

AHMADI FARHAD; KARAMIAN EHSAN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Pharmaceutical Research Year:2014 | Volume:13 | Issue:2 Page(s): 417-429

Download Full-Text

View:

295

Download:

122

Cites:

Information Journal Paper

Title

COMPUTATIONAL AIDED-MOLECULAR IMPRINTED POLYMER DESIGN FOR SOLID PHASE EXTRACTION OF METAPROTERENOL FROM PLASMA AND DETERMINATION BY VOLTAMMETRY USING MODIFIED CARBON NANOTUBE ELECTRODE

Author(s)

AHMADI FARHAD | KARAMIAN EHSAN | Issue Writer Certificate

Keywords

DOPING CONTROL

METAPROTERENOL

COMPUTATIONAL MOLECULAR MODELING

MOLECULARLY IMPRINTED POLYMER

MODIFIED CARBON NANO TUBE ELECTRODE

Abstract

A molecular imprinted polymer (MIP) was computationally designed and synthesized for the selective extraction of METAPROTERENOL (MTP), from human plasma. In this regards semi empirical MP3 and mechanical quantum (DFT) calculations were used to find a suitable functional monomers. On the basis of computational and experimental results, acrylic acid (AA) and DMSO: MeOH (90: 10 %V/V) were found to be the best choices of functional monomer and polymerization solvents, respectively. This polymer was then used as a selective sorbent to develop a molecularly imprinted solid-phase extraction (MISPE) procedure followed by differential pulse voltammetry by using modified carbon nanotube electrode. The analysis was performed in phosphate buffer, pH 7.0. Peak currents were measured at+0.67 V versus Ag/ AgCl. The linear calibration range was 0.026–8.0 mg mL-1 with a limit of detection 0.01 mg mL-1. The relative standard deviation at 0.5 mg mL-1 was 4.76% (n=5). The mean recoveries of 5 mg mL-1 MTP from plasma was 92.2% (n=5). The data of MISPE-DPV were compared with the MISPE-HPLC-UV. Although, the MISPE-DPV was more sensitive but both techniques have similar accuracy and precision.

Cites

No record.

References

No record.

Cite

APA: Copy

AHMADI, FARHAD, & KARAMIAN, EHSAN. (2014). COMPUTATIONAL AIDED-MOLECULAR IMPRINTED POLYMER DESIGN FOR SOLID PHASE EXTRACTION OF METAPROTERENOL FROM PLASMA AND DETERMINATION BY VOLTAMMETRY USING MODIFIED CARBON NANOTUBE ELECTRODE. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 13(2), 417-429. SID. https://sid.ir/paper/288243/en

Vancouver: Copy

AHMADI FARHAD, KARAMIAN EHSAN. COMPUTATIONAL AIDED-MOLECULAR IMPRINTED POLYMER DESIGN FOR SOLID PHASE EXTRACTION OF METAPROTERENOL FROM PLASMA AND DETERMINATION BY VOLTAMMETRY USING MODIFIED CARBON NANOTUBE ELECTRODE. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2014;13(2):417-429. Available from: https://sid.ir/paper/288243/en

IEEE: Copy

FARHAD AHMADI, and EHSAN KARAMIAN, “COMPUTATIONAL AIDED-MOLECULAR IMPRINTED POLYMER DESIGN FOR SOLID PHASE EXTRACTION OF METAPROTERENOL FROM PLASMA AND DETERMINATION BY VOLTAMMETRY USING MODIFIED CARBON NANOTUBE ELECTRODE,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 13, no. 2, pp. 417–429, 2014, [Online]. Available: https://sid.ir/paper/288243/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops