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Information Journal Paper

Title

EFFECT OF DEXAMETHASONE, INSULIN AND EGF ON THE MYOGENIC POTENTIAL ON HUMAN ENDOMETRIAL STEM CELL

Pages

  659-664

Abstract

 Human endometrium contains mesenchymal stem cells (eMSC) which have the ability to differentiate into three cell lineages and the potential in therapeutic applications. We hypothesize that using environmental induction in culture media such as DEXAMETHASONE, human recombinant insulin and human epidermal growth factor (hEGF) can differentiate ENDOMETRIAL STEM CELLs into myoblast. These agents have a broad range of effects in myoblast DIFFERENTIATION in-vitro. We used immunohistochemistry analysis and RT -PCR to evaluate the presence of skeletal muscle - specific proteins some of which are expressed in the early stage of DIFFERENTIATION including myoD and Desmin which expressed at later stages of DIFFERENTIATION. In conclusion eMSC can differentiate in culture media which contains above mentioned factors and use for therapeutic purpose in muscular degenerative disease.

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    APA: Copy

    JALALI TEHRANI, HORA, PARIVAR, KAZEM, AI, JAFAR, KAJBAFZADEH, ABDOL MOHAMMAD, RAHBARGHAZI, REZA, HASHEMI, MEHRDAD, & SADEGHIZADEH, MAJID. (2014). EFFECT OF DEXAMETHASONE, INSULIN AND EGF ON THE MYOGENIC POTENTIAL ON HUMAN ENDOMETRIAL STEM CELL. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 13(2), 659-664. SID. https://sid.ir/paper/288247/en

    Vancouver: Copy

    JALALI TEHRANI HORA, PARIVAR KAZEM, AI JAFAR, KAJBAFZADEH ABDOL MOHAMMAD, RAHBARGHAZI REZA, HASHEMI MEHRDAD, SADEGHIZADEH MAJID. EFFECT OF DEXAMETHASONE, INSULIN AND EGF ON THE MYOGENIC POTENTIAL ON HUMAN ENDOMETRIAL STEM CELL. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2014;13(2):659-664. Available from: https://sid.ir/paper/288247/en

    IEEE: Copy

    HORA JALALI TEHRANI, KAZEM PARIVAR, JAFAR AI, ABDOL MOHAMMAD KAJBAFZADEH, REZA RAHBARGHAZI, MEHRDAD HASHEMI, and MAJID SADEGHIZADEH, “EFFECT OF DEXAMETHASONE, INSULIN AND EGF ON THE MYOGENIC POTENTIAL ON HUMAN ENDOMETRIAL STEM CELL,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 13, no. 2, pp. 659–664, 2014, [Online]. Available: https://sid.ir/paper/288247/en

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