Amperometric Determination of Ascorbic Acid in Pharmaceutical Formulations by a Reduced Graphene Oxide-cobalt Hexacyanoferrate Nanocomposite

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HELI HOSSEIN; SATTARAHMADY NAGHMEH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Iranian Journal of Pharmaceutical Research Year:2015 | Volume:14 | Issue:2 Page(s): 453-463

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Title

Amperometric Determination of Ascorbic Acid in Pharmaceutical Formulations by a Reduced Graphene Oxide-cobalt Hexacyanoferrate Nanocomposite

Author(s)

HELI HOSSEIN | SATTARAHMADY NAGHMEH | Issue Writer Certificate

Keywords

Reduced graphene oxide

Cobalt hexacyanoferrate

Nanocomposite

Ascorbic acid

Electroanalysis

Abstract

Investigation of the redox properties of drugs and their determination are performed by electrochemical techniques. Data obtained from electrochemical techniques are often correlated with molecular structure and pharmacological activity of drugs. In this regard, different modified electrodes were applied as sensors for quantification of different drugs. A Nanocomposite of Reduced graphene oxide-Cobalt hexacyanoferrate was synthesized by a simple precipitation route. Scanning electron microscopy revealed that the Nanocomposite comprised nanoparticles of Cobalt hexacyanoferrate attached to the Reduced graphene oxide nanosheets. A Nanocomposite-modified carbon paste electrode was then fabricated. It represented prominent activity toward the electrocatalytic oxidation of Ascorbic acid, and the kinetics of the electrooxidation process was evaluated. Finally, an amperometric method was developed for the quantification of Ascorbic acid in different pharmaceutical formulations.

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APA: Copy

HELI, HOSSEIN, & SATTARAHMADY, NAGHMEH. (2015). Amperometric Determination of Ascorbic Acid in Pharmaceutical Formulations by a Reduced Graphene Oxide-cobalt Hexacyanoferrate Nanocomposite. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 14(2), 453-463. SID. https://sid.ir/paper/288466/en

Vancouver: Copy

HELI HOSSEIN, SATTARAHMADY NAGHMEH. Amperometric Determination of Ascorbic Acid in Pharmaceutical Formulations by a Reduced Graphene Oxide-cobalt Hexacyanoferrate Nanocomposite. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2015;14(2):453-463. Available from: https://sid.ir/paper/288466/en

IEEE: Copy

HOSSEIN HELI, and NAGHMEH SATTARAHMADY, “Amperometric Determination of Ascorbic Acid in Pharmaceutical Formulations by a Reduced Graphene Oxide-cobalt Hexacyanoferrate Nanocomposite,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 14, no. 2, pp. 453–463, 2015, [Online]. Available: https://sid.ir/paper/288466/en

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