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Information Journal Paper

Title

The Effects of Ginger on Fasting Blood Sugar, Hemoglobin A1c, Apolipoprotein B, Apolipoprotein A-I and Malondialdehyde in Type 2 Diabetic Patients

Pages

  131-140

Abstract

 Diabetes mellitus is the most common endocrine disorder, causes many complications such as micro-and macro-vascular diseases. Anti-diabetic, hypolipidemic and anti-oxidative properties of Ginger have been noticed in several researches. The present study was conducted to investigate the effects of Ginger on fasting blood sugar, Hemoglobin A1c, apolipoprotein B, apolipoprotein A-I, and Malondialdehyde in type 2 diabetic patients. In a randomized, double-blind, placebo-controlled, clinical trial, a total of 41 type 2 diabetic patients randomly were assigned to Ginger or placebo groups (22 in Ginger group and 19 in control group), received 2 g/day of Ginger powder supplement or lactose as placebo for 12 weeks. The serum concentrations of fasting blood sugar, Hemoglobin A1c, apolipoprotein B, apolipoprotein A-I and Malondialdehyde were analyzed before and after the intervention. Ginger supplementation significantly reduced the levels of fasting blood sugar, hemoglobin A1c, apolipoprotein B, apolipoprotein B/apolipoprotein A-I and Malondialdehyde in Ginger group in comparison to baseline, as well as control group, while it increased the level of apolipoprotein A-I (p<0. 05). It seems that oral administration of Ginger powder supplement can improves fasting blood sugar, hemoglobin A1c, apolipoprotein B, apolipoprotein A-I, apolipoprotein B/apolipoprotein A-I and Malondialdehyde in type 2 diabetic patients. So it may have a role in alleviating the risk of some chronic complications of diabetes.

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    APA: Copy

    KHANDOUZI, NAFISEH, SHIDFAR, FARZAD, RAJAB, ASADOLLAH, Rahideh, Tayebeh, HOSSEINI, PAYAM, & Mir Taheri, Mohsen. (2015). The Effects of Ginger on Fasting Blood Sugar, Hemoglobin A1c, Apolipoprotein B, Apolipoprotein A-I and Malondialdehyde in Type 2 Diabetic Patients. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 14(1), 131-140. SID. https://sid.ir/paper/288496/en

    Vancouver: Copy

    KHANDOUZI NAFISEH, SHIDFAR FARZAD, RAJAB ASADOLLAH, Rahideh Tayebeh, HOSSEINI PAYAM, Mir Taheri Mohsen. The Effects of Ginger on Fasting Blood Sugar, Hemoglobin A1c, Apolipoprotein B, Apolipoprotein A-I and Malondialdehyde in Type 2 Diabetic Patients. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2015;14(1):131-140. Available from: https://sid.ir/paper/288496/en

    IEEE: Copy

    NAFISEH KHANDOUZI, FARZAD SHIDFAR, ASADOLLAH RAJAB, Tayebeh Rahideh, PAYAM HOSSEINI, and Mohsen Mir Taheri, “The Effects of Ginger on Fasting Blood Sugar, Hemoglobin A1c, Apolipoprotein B, Apolipoprotein A-I and Malondialdehyde in Type 2 Diabetic Patients,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 14, no. 1, pp. 131–140, 2015, [Online]. Available: https://sid.ir/paper/288496/en

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