BIOLOGICAL ACTIVITY AND PHYTOCHEMICAL STUDY OF SCUTELLARIA PLATYSTEGIA

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MADANI mousavi Seyedeh Neda; DELAZAR ABBAS; NAZEMIYEH HOSSEIN; KHODAIE LALEH

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Pharmaceutical Research Year:2015 | Volume:14 | Issue:1 Page(s): 215-223

Download Full-Text

View:

307

Download:

Cites:

Information Journal Paper

Title

BIOLOGICAL ACTIVITY AND PHYTOCHEMICAL STUDY OF SCUTELLARIA PLATYSTEGIA

Author(s)

MADANI mousavi Seyedeh Neda | DELAZAR ABBAS | NAZEMIYEH HOSSEIN | KHODAIE LALEH | Issue Writer Certificate

Keywords

Scutellaria platystegia

Antimalaria

Antioxidant

DPPH

Labiatae

Abstract

This study aimed to determine biological activity and phytochemical study of Scutellaria platystegia (family Labiatae). Methanolic (MeOH) extract of aerial parts of S. platystegia and SPE fractions of methanolic extract (specially 20% and 40% methanolic fractions), growing in East-Azarbaijan province of Iran were found to have radical scavenging activity by DPPH (2, 2-diphenyl-1-pycryl hydrazyl) assay. Dichloromethane (DCM) extract of this plant exhibited animalarial activity by cell free method providing IC50 at 1. 1876 mg/mL. Crude extracts did not exhibit any toxicity assessed by brine shrimp lethality assay. Phytochemical study of methanolic extract by using reverse phase HPLC method and NMR instrument for isolation and identification of pure compounds respectively, yielded 2-(4-hydroxy phenyl) ethyl-O-β-D-glucopyranoside from 10% and apigenin 7-O-glucoside, verbascoside and martynoside from 40% SPE fraction. Occurance of verbascoside and martynoside as biochemical markers appeared to be widespread in this genus. Antioxidant and Antimalarial activity of MeOH and DCM extracts, respectively, as well as no general toxicity of them could provide a basis for further in-vitro and in-vivo studies and clinical trials to develop new therapeutical alternatives.

Cites

PHENOLIC DERIVATIVES OF ARTEMISIA SPICIGERA C. KOCH GROWING IN IRAN

References

No record.

Cite

APA: Copy

MADANI mousavi, Seyedeh Neda, DELAZAR, ABBAS, NAZEMIYEH, HOSSEIN, & KHODAIE, LALEH. (2015). BIOLOGICAL ACTIVITY AND PHYTOCHEMICAL STUDY OF SCUTELLARIA PLATYSTEGIA. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 14(1), 215-223. SID. https://sid.ir/paper/288500/en

Vancouver: Copy

MADANI mousavi Seyedeh Neda, DELAZAR ABBAS, NAZEMIYEH HOSSEIN, KHODAIE LALEH. BIOLOGICAL ACTIVITY AND PHYTOCHEMICAL STUDY OF SCUTELLARIA PLATYSTEGIA. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2015;14(1):215-223. Available from: https://sid.ir/paper/288500/en

IEEE: Copy

Seyedeh Neda MADANI mousavi, ABBAS DELAZAR, HOSSEIN NAZEMIYEH, and LALEH KHODAIE, “BIOLOGICAL ACTIVITY AND PHYTOCHEMICAL STUDY OF SCUTELLARIA PLATYSTEGIA,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 14, no. 1, pp. 215–223, 2015, [Online]. Available: https://sid.ir/paper/288500/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops