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Information Journal Paper

Title

Antibacterial Activity of Polyaniline Coated Silver Nanoparticles Synthesized from Piper Betle Leaves Extract

Pages

  591-597

Abstract

 Plants or natural resources have been found to be a good alternative method for nanoparticles synthesis. In this study, polyaniline coated Silver Nanoparticles (AgNPs) synthesized from Piper betle leaves extract were investigated for their Antibacterial activity. Silver Nanoparticles were prepared from the reduction of silver nitrate and NaBH4 was used as reducing agent. Silver Nanoparticles and extracts were mixed thoroughly and then coated by polyaniline. Prepared nanoparticles were characterized by Visual inspection, Ultraviolet-visible spectroscopy (UV), Fourier transform infrared Spectroscopy (FT-IR), Transmission Electron Microscopy (TEM) techniques. Antibacterial activities of the synthesized Silver Nanoparticles were tested against Staphylococcus aureus ATCC 25923, Salmonella typhi ATCC 14028, Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATCC 27853. UV– Vis spectrum of reaction mixture showed strong absorption peak with centering at 400 nm. The FT-IR results imply that Ag-NPs were successfully synthesized and capped with bio-compounds present in P. betle. TEM image showed that Ag-NPs formed were well dispersed with a spherical structures and particle size ranging from 10 to 30 nm. The result revealed that Ag-Extract NPs showed 32. 78± 0. 64 mm Zone of inhibition against S. aureus, whereas norfloxacin (positive control) showed maximum 32. 15± 0. 40 mm Zone of inhibition for S. aureus. Again, maximum Zone of inhibition 29. 55± 0. 45 mm was found for S. typhi, 27. 12± 0. 38 mm for E. coli and 21. 95± 0. 45 mm for P. aeruginosa. The results obtained by this study can’ t be directly extrapolated to human; so further studies should be undertaken to established the strong antimicrobial activity of Ag-Extract NPs for drug development program.

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    APA: Copy

    Or Rashid, Md.Mamun, Islam, Md.Shafiul, Haque, Md.Azizul, Rahman, Md.Arifur, Hossain, Md.Tanvir, & Hamid, Md.Abdul. (2016). Antibacterial Activity of Polyaniline Coated Silver Nanoparticles Synthesized from Piper Betle Leaves Extract. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 15(2), 591-597. SID. https://sid.ir/paper/288608/en

    Vancouver: Copy

    Or Rashid Md.Mamun, Islam Md.Shafiul, Haque Md.Azizul, Rahman Md.Arifur, Hossain Md.Tanvir, Hamid Md.Abdul. Antibacterial Activity of Polyaniline Coated Silver Nanoparticles Synthesized from Piper Betle Leaves Extract. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2016;15(2):591-597. Available from: https://sid.ir/paper/288608/en

    IEEE: Copy

    Md.Mamun Or Rashid, Md.Shafiul Islam, Md.Azizul Haque, Md.Arifur Rahman, Md.Tanvir Hossain, and Md.Abdul Hamid, “Antibacterial Activity of Polyaniline Coated Silver Nanoparticles Synthesized from Piper Betle Leaves Extract,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 15, no. 2, pp. 591–597, 2016, [Online]. Available: https://sid.ir/paper/288608/en

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