MEDICATION INTERACTION AND PHYSICIANSꞌ COMPLIANCE ASSESSMENT THROUGH MEDICATION RECONCILIATION FORMS IN A UNIVERSITY AFFILIATED HOSPITAL

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TALEBI MOHAMMAD MEHDI; SEFIDANI FOROUGH AIDA; RIAZI ESFAHANI PARSA; ESKANDARI RAHA; HAGHGOO ROODABEH; FAHIMI FANAK

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Journal: Iranian Journal of Pharmaceutical Research Year:2018 | Volume:17 | Issue:SUPPLEMENT Page(s): 159-167

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Title

MEDICATION INTERACTION AND PHYSICIANSꞌ COMPLIANCE ASSESSMENT THROUGH MEDICATION RECONCILIATION FORMS IN A UNIVERSITY AFFILIATED HOSPITAL

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Keywords

ADVERSE DRUG REACTION

MEDICATION DISCREPANCIES

MEDICATION RECONCILIATION

MEDICATION ERROR

DRUG INTERACTIONS

Abstract

Medication interactions are associated with various unwanted ADVERSE DRUG REACTIONs. MEDICATION RECONCILIATION involves a process in which a complete list of patient's previously prescribed medications are recorded and subsequently evaluated within the context of concomitantly prescribed medications and present medical condition during the hospitalization. Medical records of randomly selected 270 patients hospitalized in internal medicine, cardiovascular and infectious diseases wards were evaluated. DRUG INTERACTIONS were checked by LexiCompÒ database. Each interaction was assigned a risk rating of A, B, C, D, or X. The progression from A to X was based on increased urgency for responding to the data. Completed reconciliation forms were attached to patient charts for evaluation of physicians' compliance. DRUG INTERACTIONS were observed in 65.2% (176/270) of cases. The risk rating of interactions was categorized as C, D and X in 54.2%, 32.4%, and 13.4% of cases, respectively. There was a positive correlation between the number of prescribed medications and the rate of interactions (p -value<0.001, Kendall's correlation coefficient=0.487). Moreover, the length of hospitalization and the rate of DRUG INTERACTIONS were significantly correlated (p -value<0.001, Kendall's correlation coefficient=0.350). Cardiovascular agents constituted the largest proportion of interactions (25%) followed by antibiotics (18%) and immunosuppressive agents (6%). In 59.6% of cases, no corrective action was taken by the physicians. MEDICATION DISCREPANCIES occur commonly in hospital settings. Structured MEDICATION RECONCILIATION may have a positive impact on prevention of MEDICATION ERRORs.

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APA: Copy

TALEBI, MOHAMMAD MEHDI, SEFIDANI FOROUGH, AIDA, RIAZI ESFAHANI, PARSA, ESKANDARI, RAHA, HAGHGOO, ROODABEH, & FAHIMI, FANAK. (2018). MEDICATION INTERACTION AND PHYSICIANS? COMPLIANCE ASSESSMENT THROUGH MEDICATION RECONCILIATION FORMS IN A UNIVERSITY AFFILIATED HOSPITAL. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 17(SUPPLEMENT), 159-167. SID. https://sid.ir/paper/288802/en

Vancouver: Copy

TALEBI MOHAMMAD MEHDI, SEFIDANI FOROUGH AIDA, RIAZI ESFAHANI PARSA, ESKANDARI RAHA, HAGHGOO ROODABEH, FAHIMI FANAK. MEDICATION INTERACTION AND PHYSICIANS? COMPLIANCE ASSESSMENT THROUGH MEDICATION RECONCILIATION FORMS IN A UNIVERSITY AFFILIATED HOSPITAL. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2018;17(SUPPLEMENT):159-167. Available from: https://sid.ir/paper/288802/en

IEEE: Copy

MOHAMMAD MEHDI TALEBI, AIDA SEFIDANI FOROUGH, PARSA RIAZI ESFAHANI, RAHA ESKANDARI, ROODABEH HAGHGOO, and FANAK FAHIMI, “MEDICATION INTERACTION AND PHYSICIANS? COMPLIANCE ASSESSMENT THROUGH MEDICATION RECONCILIATION FORMS IN A UNIVERSITY AFFILIATED HOSPITAL,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 17, no. SUPPLEMENT, pp. 159–167, 2018, [Online]. Available: https://sid.ir/paper/288802/en

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