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Information Journal Paper

Title

CHEMICAL COMPOSITION AND BIOLOGICAL ACTIVITIES OF METHANOLIC EXTRACT OF SCROPHULARIA OXYSEPALA BOISS

Pages

  338-346

Abstract

 Isolated five known IRIDOIDS GLYCOSIDES (Scrophuloside A, Harpagoside B, 5-hydroxyloganin, 8-O-acetylharpagide and 6-O-methyl, 1-glucopyranosyl catalpol), one phenyl ethanoid glycoside (Verbascoside) and a PHENYL ETHANOL AMINE (2- (4-Chlorobenzyl amino) ethanol) compound from the methanolic extract of aerial parts of Scrophularia oxysepala using by high performance liquid chromatographyare based on isocratic and liner gradients by C18 column. The structure elucidations of the isolated compounds were performed by spectroscopic methods including1H-NMR, 13C-NMR, 2 D NMR technique such as HMBC (in deuterated methanol as solvent), GC-MS and UV, also methanolic extract and fractions (fractionated on solid phase extraction on C18 cartridge (Spack-C18)) of this plant was tested for free RADICAL SCAVENGING properties toward the 1, 1-diphenyl-1-picrylhydrazyl (DPPH), GENERAL TOXICITY (Brine shrimp toxicity assay), insecticidal (Contact toxicity insecticidal assay) and antimalarial activities (hemebiocrystallization inhibition assay).

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    • Cite

    APA: Copy

    PASDARAN, ARDALAN, DELAZAR, ABBAS, Ayatollahi, Seyed Abdulmajid, & PASDARAN, ARSALAN. (2017). CHEMICAL COMPOSITION AND BIOLOGICAL ACTIVITIES OF METHANOLIC EXTRACT OF SCROPHULARIA OXYSEPALA BOISS. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 16(1), 338-346. SID. https://sid.ir/paper/288807/en

    Vancouver: Copy

    PASDARAN ARDALAN, DELAZAR ABBAS, Ayatollahi Seyed Abdulmajid, PASDARAN ARSALAN. CHEMICAL COMPOSITION AND BIOLOGICAL ACTIVITIES OF METHANOLIC EXTRACT OF SCROPHULARIA OXYSEPALA BOISS. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2017;16(1):338-346. Available from: https://sid.ir/paper/288807/en

    IEEE: Copy

    ARDALAN PASDARAN, ABBAS DELAZAR, Seyed Abdulmajid Ayatollahi, and ARSALAN PASDARAN, “CHEMICAL COMPOSITION AND BIOLOGICAL ACTIVITIES OF METHANOLIC EXTRACT OF SCROPHULARIA OXYSEPALA BOISS,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 16, no. 1, pp. 338–346, 2017, [Online]. Available: https://sid.ir/paper/288807/en

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