DEVELOPMENT OF AN ANALYTICAL METHOD FOR DIBUTYL PHTHALATE DETERMINATION USING SURROGATE ANALYTE APPROACH

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FARZANEHFAR VAHID; FAIZI MEHRDAD; NADERI NIMA; KOBARFARD FARZAD

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Journal Paper

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Journal: Iranian Journal of Pharmaceutical Research Year:2017 | Volume:16 | Issue:1 Page(s): 140-145

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Title

DEVELOPMENT OF AN ANALYTICAL METHOD FOR DIBUTYL PHTHALATE DETERMINATION USING SURROGATE ANALYTE APPROACH

Author(s)

FARZANEHFAR VAHID | FAIZI MEHRDAD | NADERI NIMA | KOBARFARD FARZAD | Issue Writer Certificate

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Abstract

Dibutyl phthalate (DBP) is a phthalic acid ester and is widely used in polymeric products to make them more flexible. DBP is found in almost every plastic material and is believed to be persistent in the environment. Various analytical methods have been used to measure DBP in different matrices. Considering the ubiquitous nature of DBP, the most important challenge in DBP analyses is the contamination of even analytical grade organic solvents with this compound and lack of availability of a true blank matrix to construct the calibration line. Standard addition method or using artificial matrices reduce the precision and accuracy of the results. In this study a surrogate analyte approach that is based on using deuterium labeled analyte (DBP-d4) to construct the calibration line was applied to determine DBP in hexane samples.

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APA: Copy

FARZANEHFAR, VAHID, FAIZI, MEHRDAD, NADERI, NIMA, & KOBARFARD, FARZAD. (2017). DEVELOPMENT OF AN ANALYTICAL METHOD FOR DIBUTYL PHTHALATE DETERMINATION USING SURROGATE ANALYTE APPROACH. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 16(1), 140-145. SID. https://sid.ir/paper/288819/en

Vancouver: Copy

FARZANEHFAR VAHID, FAIZI MEHRDAD, NADERI NIMA, KOBARFARD FARZAD. DEVELOPMENT OF AN ANALYTICAL METHOD FOR DIBUTYL PHTHALATE DETERMINATION USING SURROGATE ANALYTE APPROACH. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2017;16(1):140-145. Available from: https://sid.ir/paper/288819/en

IEEE: Copy

VAHID FARZANEHFAR, MEHRDAD FAIZI, NIMA NADERI, and FARZAD KOBARFARD, “DEVELOPMENT OF AN ANALYTICAL METHOD FOR DIBUTYL PHTHALATE DETERMINATION USING SURROGATE ANALYTE APPROACH,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 16, no. 1, pp. 140–145, 2017, [Online]. Available: https://sid.ir/paper/288819/en

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