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Information Journal Paper

Title

Fast Electrocatalytic Determination of Methimazole at an Activated Glassy Carbon Electrode

Pages

  735-741

Abstract

 A fast and simple voltammetric method for the determination of Methimazole in pharmaceutical products was reported. A glassy carbon electrode was pretreated by anodization at +1. 75 V (vs. SCE) for 5 min, followed by potential cycling in the range of 0. 3-1. 3 V (20 cycles). The pretreated electrode showed an excellent electrocatalytic effect on the oxidation of Methimazole. Compared with untreated electrode, a large decrease (~300 mV) in the oxidation peak of Methimazole was observed. The oxidation peak current at the new potential (0. 4 V vs. SCE) was linearly dependent on the concentration of Methimazole in the range of 7. 0-130 μ M with a detection limit of 3. 7 μ M (S/N = 3). The method was successfully used in the determination of Methimazole in thyramozol Tablets. Due to the simple and fast electrode preparation, there is no need for electrode cleaning or storage.

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    APA: Copy

    JALALI, FAHIMEH, & HATAMI, ZAHRA. (2016). Fast Electrocatalytic Determination of Methimazole at an Activated Glassy Carbon Electrode. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 15(4), 735-741. SID. https://sid.ir/paper/289067/en

    Vancouver: Copy

    JALALI FAHIMEH, HATAMI ZAHRA. Fast Electrocatalytic Determination of Methimazole at an Activated Glassy Carbon Electrode. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2016;15(4):735-741. Available from: https://sid.ir/paper/289067/en

    IEEE: Copy

    FAHIMEH JALALI, and ZAHRA HATAMI, “Fast Electrocatalytic Determination of Methimazole at an Activated Glassy Carbon Electrode,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 15, no. 4, pp. 735–741, 2016, [Online]. Available: https://sid.ir/paper/289067/en

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