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Information Journal Paper

Title

Fingerprint Analysis and Quantitative Determination of Fourteen Active Components in the Traditional Chinese Medicinal Preparation Feiyang changweiyan Capsule by HPLC-DAD-ESI-MS/MS

Pages

  948-960

Abstract

 FeiYangchangweiyan capsule (FY capsule), a traditional Chinese medicinal preparation consisting of three medicinal herbs, has been used to treat bacterial dysentery, acute, and chronic gastroenteritis for several decades. In this study, a novel, convenient, accurate, and valid method was developed by using high-performance liquid chromatography (HPLC) coupled with diode array detection (DAD) to obtain a chromatographic Fingerprint of FeiYangchangweiyan capsule (FY capsule). Then, fourteen peaks were identified according to MS/MS fragmentation behavior of the reference standards by using HPLC-DAD-ESI-MS/MS analysis. At the same time, the Fingerprint similarity was calculated and the contents of known ingredients were also determined simultaneously. The result demonstrated that the HPLC Fingerprint combining similarity evaluation and quantification analysis can be successfully applied to control the quality of FY capsule.

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    APA: Copy

    ZHOU, DAN, YANG, QIAN, Yu, Zhe, Chang, Ying, Tian, Tian, Shi, Zhi Hui, Dong, Hong Liang, Li, Hua, GUO, JUN, & Wang, Si Wang. (2019). Fingerprint Analysis and Quantitative Determination of Fourteen Active Components in the Traditional Chinese Medicinal Preparation Feiyang changweiyan Capsule by HPLC-DAD-ESI-MS/MS. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 18(2), 948-960. SID. https://sid.ir/paper/289135/en

    Vancouver: Copy

    ZHOU DAN, YANG QIAN, Yu Zhe, Chang Ying, Tian Tian, Shi Zhi Hui, Dong Hong Liang, Li Hua, GUO JUN, Wang Si Wang. Fingerprint Analysis and Quantitative Determination of Fourteen Active Components in the Traditional Chinese Medicinal Preparation Feiyang changweiyan Capsule by HPLC-DAD-ESI-MS/MS. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2019;18(2):948-960. Available from: https://sid.ir/paper/289135/en

    IEEE: Copy

    DAN ZHOU, QIAN YANG, Zhe Yu, Ying Chang, Tian Tian, Zhi Hui Shi, Hong Liang Dong, Hua Li, JUN GUO, and Si Wang Wang, “Fingerprint Analysis and Quantitative Determination of Fourteen Active Components in the Traditional Chinese Medicinal Preparation Feiyang changweiyan Capsule by HPLC-DAD-ESI-MS/MS,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 18, no. 2, pp. 948–960, 2019, [Online]. Available: https://sid.ir/paper/289135/en

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