COMPMISON OF ANTI-CMV (IGG-IGM) SEROLOGIC PREVALENCE AMONG CONTROLS AND PATIENTS

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TARABADI F.A.; BABAEIE GH.; HASHEMI E.; BOROUMAND BEHROUZ; SHAIGAN MOZHGAN

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Journal: Hakim Journal Year:2002 | Volume:4 | Issue:4 Page(s): 243-247

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Title

COMPMISON OF ANTI-CMV (IGG-IGM) SEROLOGIC PREVALENCE AMONG CONTROLS AND PATIENTS

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Keywords

CYTOMEGALOVIMSQ4

HEMODIALYSISQ4

RENAL TRANSPLANTATIONQ4

INFECTIOUS DISEASEQ4

Abstract

CMV belongs to Herpes viridae family and it is the largest human virus. Prevalence of CMV depends on age, geographic and socioeconomic factors. For about three decades, CMV infection has been recognized to be a complication of transfusion in an immature or compromised immune system. If a transplant candidate has not been infected with CMV and no CMV specific antibodies can be detected by serology. Primary infection could be transmitted via transfusion or transplantation. In this study using serologic tests, we detected anti-CMV (IgM, IgG) antibodies (with ELISA) in 128 renal transplant candidates who were under intermittent HEMODIALYSIS and 500 blood donors, as controls. About 89.8% of transplant candidates and 86% of normal individuals were IgG positive. Statistical analysis showed no significant difference between these two groups. 2.3% of transplant candidates and 0.4% of normal individuals were positive for IgM There was significant difference in IgM between these two groups (P<0.01). This difference is due to transmission of CMV by transfusion as a primary infection or reactivating of latent virus because of immunosuppressed state in these patients. Policies and procedures to control transmission of this virus, follow up of high risk patients and appropriate therapy are critical for CMV syndrome prevention.

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APA: Copy

TARABADI, F.A., BABAEIE, GH., HASHEMI, E., BOROUMAND, BEHROUZ, & SHAIGAN, MOZHGAN. (2002). COMPMISON OF ANTI-CMV (IGG-IGM) SEROLOGIC PREVALENCE AMONG CONTROLS AND PATIENTS. HAKIM RESEARCH JOURNAL, 4(4), 243-247. SID. https://sid.ir/paper/29095/en

Vancouver: Copy

TARABADI F.A., BABAEIE GH., HASHEMI E., BOROUMAND BEHROUZ, SHAIGAN MOZHGAN. COMPMISON OF ANTI-CMV (IGG-IGM) SEROLOGIC PREVALENCE AMONG CONTROLS AND PATIENTS. HAKIM RESEARCH JOURNAL[Internet]. 2002;4(4):243-247. Available from: https://sid.ir/paper/29095/en

IEEE: Copy

F.A. TARABADI, GH. BABAEIE, E. HASHEMI, BEHROUZ BOROUMAND, and MOZHGAN SHAIGAN, “COMPMISON OF ANTI-CMV (IGG-IGM) SEROLOGIC PREVALENCE AMONG CONTROLS AND PATIENTS,” HAKIM RESEARCH JOURNAL, vol. 4, no. 4, pp. 243–247, 2002, [Online]. Available: https://sid.ir/paper/29095/en

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