HTLV-I INFECTION: VIRUS STRUCTURE, IMMUNE RESPONSE TO THE VIRUS AND GENETIC ASSOCIATION STUDIES IN HTLV-I-INFECTED INDIVIDUALS

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RAFATPANAH H.; FARID R.; GOLANBAR G.; JABARI AZAD F.

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Journal Paper

Paper Information

Journal: Iranian Journal of Allergy, Asthma and Immunology Year:2006 | Volume:5 | Issue:4 Page(s): 153-166

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Information Journal Paper

Title

HTLV-I INFECTION: VIRUS STRUCTURE, IMMUNE RESPONSE TO THE VIRUS AND GENETIC ASSOCIATION STUDIES IN HTLV-I-INFECTED INDIVIDUALS

Author(s)

RAFATPANAH H. | FARID R. | GOLANBAR G. | JABARI AZAD F. | Issue Writer Certificate

Keywords

CTL RESPONSE

CYTOKINE GENE POLYMORPHISM

HAM/TSP

HTLV-I

MHC

Abstract

Although the structure of human T lymphoptropic virus type I (HTLV-I) has been known well, the function of some proteins encoded by HTLV-I PX region is not fully understood. Furthermore, the responses of the immune system to HTLV-I remain still unknown. Most of HTLV-I-infected individuals show a strong and persistently activated cytotoxic T-cell (CTL) response to the virus. The frequency of HTLV-I specific CTL is higher in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) compared with HTLV-I carriers. However, the efficacy of the immune response determines the outcome of HTLV-I-associated diseases. Among the risk factors which contribute to the observed differences between HAM/TSP patients and HTLV-I carriers, the interaction between different genes and/or environmental factors seem to be important. These factors may also involve in outcome of HTLV-I infection in infected-individuals.

Cites

PREVALENCE OF HUMAN T-LYMPHOTROPIC VIRUS TYPES I AND II IN PATIENTS WITH HEMATOLOGICAL DISORDERS IN ISFAHAN, IRAN

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APA: Copy

RAFATPANAH, H., FARID, R., GOLANBAR, G., & JABARI AZAD, F.. (2006). HTLV-I INFECTION: VIRUS STRUCTURE, IMMUNE RESPONSE TO THE VIRUS AND GENETIC ASSOCIATION STUDIES IN HTLV-I-INFECTED INDIVIDUALS. IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI), 5(4), 153-166. SID. https://sid.ir/paper/291141/en

Vancouver: Copy

RAFATPANAH H., FARID R., GOLANBAR G., JABARI AZAD F.. HTLV-I INFECTION: VIRUS STRUCTURE, IMMUNE RESPONSE TO THE VIRUS AND GENETIC ASSOCIATION STUDIES IN HTLV-I-INFECTED INDIVIDUALS. IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI)[Internet]. 2006;5(4):153-166. Available from: https://sid.ir/paper/291141/en

IEEE: Copy

H. RAFATPANAH, R. FARID, G. GOLANBAR, and F. JABARI AZAD, “HTLV-I INFECTION: VIRUS STRUCTURE, IMMUNE RESPONSE TO THE VIRUS AND GENETIC ASSOCIATION STUDIES IN HTLV-I-INFECTED INDIVIDUALS,” IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI), vol. 5, no. 4, pp. 153–166, 2006, [Online]. Available: https://sid.ir/paper/291141/en

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