DENDRITIC CELLS BEARING HLA-G INHIBIT T-CELL ACTIVATION IN TYPE 1 DIABETES

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ABEDIAN KENARI S.; ESLAMI M.B.; SARRAFNEJAD A.; MOHSENI M; ARDESHIR LARIJANI MOHAMMAD BAGHER

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Allergy, Asthma and Immunology Year:2007 | Volume:6 | Issue:1 Page(s): 1-7

Download Full-Text

View:

380

Download:

129

Cites:

Information Journal Paper

Title

DENDRITIC CELLS BEARING HLA-G INHIBIT T-CELL ACTIVATION IN TYPE 1 DIABETES

Author(s)

Keywords

AUTOIMMUNITY

DIABETES TYPE 1

DENDRITIC CELL

HLA-G

IFN-Β (INTERFERON Β)

Abstract

HLA-G is normally expressed on human trophoblast cells. It is a non-classical MHC molecule class I b. The role of HLA-G in diabetic type 1 is not known. We investigated the role of IFN-b in induction HLA-G expression on the monocyte derived DENDRITIC CELLs (DC) in DIABETES TYPE 1. Treatment of DENDRITIC CELL with IFN-b in vitro from diabetic patients (n=20) and normal subjects (n=20) resulted to the production and expression of HLA-G on these cells from both groups. However, comparison of DC from the diabetic patients with DC from the controls revealed lower levels of HLA-G molecules in DC from diabetic patients. Using mixed lymphocyte reaction (MLR), it was found that DC expressing HLA-G mediated the inhibition of autologous T cell activation. It is concluded that IFN-b can increase HLA-G in DC from diabetic patients; subsequently it may prevent the immune regularly pathway in the diabetic pathogenesis.

Cites

HLA-G5 AND G7 ISOFORMS IN PREGNANT WOMEN (BRIEF COMMUNICATION)

References

No record.

Cite

APA: Copy

ABEDIAN KENARI, S., ESLAMI, M.B., SARRAFNEJAD, A., MOHSENI, M, & ARDESHIR LARIJANI, MOHAMMAD BAGHER. (2007). DENDRITIC CELLS BEARING HLA-G INHIBIT T-CELL ACTIVATION IN TYPE 1 DIABETES. IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI), 6(1), 1-7. SID. https://sid.ir/paper/291146/en

Vancouver: Copy

ABEDIAN KENARI S., ESLAMI M.B., SARRAFNEJAD A., MOHSENI M, ARDESHIR LARIJANI MOHAMMAD BAGHER. DENDRITIC CELLS BEARING HLA-G INHIBIT T-CELL ACTIVATION IN TYPE 1 DIABETES. IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI)[Internet]. 2007;6(1):1-7. Available from: https://sid.ir/paper/291146/en

IEEE: Copy

S. ABEDIAN KENARI, M.B. ESLAMI, A. SARRAFNEJAD, M MOHSENI, and MOHAMMAD BAGHER ARDESHIR LARIJANI, “DENDRITIC CELLS BEARING HLA-G INHIBIT T-CELL ACTIVATION IN TYPE 1 DIABETES,” IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI), vol. 6, no. 1, pp. 1–7, 2007, [Online]. Available: https://sid.ir/paper/291146/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops