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Information Journal Paper

Title

ADVANCES IN UNDERSTANDING THE PATHOGENESIS OF EPSTEIN-BARR VIRUS-ASSOCIATED LYMPHOPROLIFERATIVE DISORDERS

Pages

  462-471

Abstract

EPSTEIN-BARR VIRUS (EBV) was discovered 50 years ago from an African Burkitt lymphoma cell line. EBV-associated LYMPHOPROLIFERATIVE DISORDERs (LPDs) are life-threatening diseases, especially in children. In this article, we review EBV-associated LPDs, especially in the area of PRIMARY IMMUNODEFICIENCY DISEASE (PID). We searched PubMed for publications with key words including EBV infection, lymphoma, LPDs and PID, and selected the manuscripts written in English that we judged to be relevant to the topic of this review. On the basis of the data in the literature, we grouped the EBV-associated LPDs into four categories: nonmalignant disease, malignant disease, acquired immunodeficiency disease and PID. Each category has its own risk factor for LPD development. EBV-associated LPD is a complex disease, creating new challenges for diagnosis and treatment.

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  • Cite

    APA: Copy

    YANG, XI, NISHIDA, NAONORI, ZHAO, XIAODONG, & KANEGANE, HIROKAZU. (2015). ADVANCES IN UNDERSTANDING THE PATHOGENESIS OF EPSTEIN-BARR VIRUS-ASSOCIATED LYMPHOPROLIFERATIVE DISORDERS. IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI), 14(5), 462-471. SID. https://sid.ir/paper/291481/en

    Vancouver: Copy

    YANG XI, NISHIDA NAONORI, ZHAO XIAODONG, KANEGANE HIROKAZU. ADVANCES IN UNDERSTANDING THE PATHOGENESIS OF EPSTEIN-BARR VIRUS-ASSOCIATED LYMPHOPROLIFERATIVE DISORDERS. IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI)[Internet]. 2015;14(5):462-471. Available from: https://sid.ir/paper/291481/en

    IEEE: Copy

    XI YANG, NAONORI NISHIDA, XIAODONG ZHAO, and HIROKAZU KANEGANE, “ADVANCES IN UNDERSTANDING THE PATHOGENESIS OF EPSTEIN-BARR VIRUS-ASSOCIATED LYMPHOPROLIFERATIVE DISORDERS,” IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI), vol. 14, no. 5, pp. 462–471, 2015, [Online]. Available: https://sid.ir/paper/291481/en

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