IS THERE ANY PARAMETER HELPFUL FOR PREDICTING A SUITABLE CANDIDATE FOR MITE IMMUNOTHERAPY?

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

KARAMAN SAIT; CAN DEMET; BAHCECI ERDEM SEMIHA; NACAROGLU HIKMET TEKIN; KARKINER CANAN SULE; GUNAY ILKER

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Allergy, Asthma and Immunology Year:2016 | Volume:15 | Issue:2 Page(s): 105-111

Download Full-Text

View:

358

Download:

193

Cites:

Information Journal Paper

Title

IS THERE ANY PARAMETER HELPFUL FOR PREDICTING A SUITABLE CANDIDATE FOR MITE IMMUNOTHERAPY?

Author(s)

Keywords

ALLERGEN IMMUNOTHERAPY

ASTHMA

CHILDREN

IMMUNOGLOBULIN E

MITE

Abstract

Few biomarkers that can predict the clinical response to ALLERGEN IMMUNOTHERAPY (AIT) have been identified. The aim of the present study was to investigate parameters that could be used "in predicting the clinical response to AIT" in CHILDREN with ASTHMA caused by house dust MITEs.We evaluated 107 CHILDREN with mild persistent ASTHMA who were sensitised only to MITE aeroallergens. The study group included 47 patients who underwent a 4-to-5-year course of subcutaneous immunotherapy with standardised MITE allergenic extract. Sixty patients who had not undergone AIT but were allergic to house MITEs were included in the control group. The clinical features and laboratory parameters of patients who did and did not sustain remission were compared.Remission was achieved in 74.5% of the 47 patients in the study group and in 20% of those in the control group. In the study group, one parameter predictive of a clinical response to AIT was identified by multivariate logistic analysis. This parameter was the serum total IgE level (tIgE) at the time of diagnosis (OR 131.64 and CI 0.858–20193; p=0.032). Serum tIgE levels£339 kU/L at diagnosis were associated with an effective clinical response to AIT, with a sensitivity of 64.5% and specificity of 88.9%.We conclude that measurement of the serum tIgE level can be used as a predictive test prior to AIT in patients sensitized to MITE aeroallergens.

Cites

No record.

References

No record.

Cite

APA: Copy

KARAMAN, SAIT, CAN, DEMET, BAHCECI ERDEM, SEMIHA, NACAROGLU, HIKMET TEKIN, KARKINER, CANAN SULE, & GUNAY, ILKER. (2016). IS THERE ANY PARAMETER HELPFUL FOR PREDICTING A SUITABLE CANDIDATE FOR MITE IMMUNOTHERAPY?. IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI), 15(2), 105-111. SID. https://sid.ir/paper/291516/en

Vancouver: Copy

KARAMAN SAIT, CAN DEMET, BAHCECI ERDEM SEMIHA, NACAROGLU HIKMET TEKIN, KARKINER CANAN SULE, GUNAY ILKER. IS THERE ANY PARAMETER HELPFUL FOR PREDICTING A SUITABLE CANDIDATE FOR MITE IMMUNOTHERAPY?. IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI)[Internet]. 2016;15(2):105-111. Available from: https://sid.ir/paper/291516/en

IEEE: Copy

SAIT KARAMAN, DEMET CAN, SEMIHA BAHCECI ERDEM, HIKMET TEKIN NACAROGLU, CANAN SULE KARKINER, and ILKER GUNAY, “IS THERE ANY PARAMETER HELPFUL FOR PREDICTING A SUITABLE CANDIDATE FOR MITE IMMUNOTHERAPY?,” IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI), vol. 15, no. 2, pp. 105–111, 2016, [Online]. Available: https://sid.ir/paper/291516/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops