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Information Journal Paper

Title

The Study of Relationship between Serum Levels of Soluble fms-like Tyrosine Kinase-1 and Soluble Fibrinogen-like Protein 2 with Delayed Graft Function after Kidney Transplantation

Pages

  412-418

Abstract

 Delayed graft function (DGF) is a transplant complication which means a need to dialysis throughout the first week after transplantation. This study aimed to ascertain the relationship between the two immunomodulatory factors of soluble fms-like tyrosine kinase-1 (sFlt-1) and soluble fibrinogen-like protein 2 (sFGL-2) with DGF after transplantation. This case-control study was done in 2 groups of 58 kidney transplant patients with and without DGF. The control group included the patients who didn’ t show DGF symptoms. Then, serum levels of sFlt-1and sFGL-2 in all blood samples were measured by ELISA. Serum sFlt-1 and sFGL-2 levels were significantly higher in the DGF group compared to those in the control group (p≤ 0. 001). sFlt-1 and sFGL-2 serum levels significantly affect DGF (p<0. 001) in such a way that they may be diagnostic factors of DGF. This study showed a significant relationship between sFlt-1 as well as sFGL-2 and DGF. Therefore, plasma levels of sFlt-1 and sFGL-2 may be used as diagnostic tools to determine the risk of DGF.

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    APA: Copy

    AKBARI, HOSSEIN, HOOSHYARI, ZAHRA, Shabanitabar, Saeede, SALMANI, ALI, NIKOUEINEJAD, HASSAN, & EINOLLAHI, BEHZAD. (2019). The Study of Relationship between Serum Levels of Soluble fms-like Tyrosine Kinase-1 and Soluble Fibrinogen-like Protein 2 with Delayed Graft Function after Kidney Transplantation. IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI), 18(4), 412-418. SID. https://sid.ir/paper/291642/en

    Vancouver: Copy

    AKBARI HOSSEIN, HOOSHYARI ZAHRA, Shabanitabar Saeede, SALMANI ALI, NIKOUEINEJAD HASSAN, EINOLLAHI BEHZAD. The Study of Relationship between Serum Levels of Soluble fms-like Tyrosine Kinase-1 and Soluble Fibrinogen-like Protein 2 with Delayed Graft Function after Kidney Transplantation. IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI)[Internet]. 2019;18(4):412-418. Available from: https://sid.ir/paper/291642/en

    IEEE: Copy

    HOSSEIN AKBARI, ZAHRA HOOSHYARI, Saeede Shabanitabar, ALI SALMANI, HASSAN NIKOUEINEJAD, and BEHZAD EINOLLAHI, “The Study of Relationship between Serum Levels of Soluble fms-like Tyrosine Kinase-1 and Soluble Fibrinogen-like Protein 2 with Delayed Graft Function after Kidney Transplantation,” IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY (IJAAI), vol. 18, no. 4, pp. 412–418, 2019, [Online]. Available: https://sid.ir/paper/291642/en

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