PREVALENCE OF HCV, HBV AND HIV INFECTIONS AMONG HEMOPHILIACS

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ALAVIAN S.M.; ARDESHIRI A.; HAJARIZADEH B.

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Paper Information

Journal: Hakim Journal Year:2003 | Volume:6 | Issue:2 Page(s): 45-51

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Information Journal Paper

Title

PREVALENCE OF HCV, HBV AND HIV INFECTIONS AMONG HEMOPHILIACS

Author(s)

ALAVIAN S.M. | ARDESHIRI A. | HAJARIZADEH B. | Issue Writer Certificate

Keywords

HEPATITIS CQ4

HEPATITIS BQ4

HIVQ4

HEMOPHILIAQ4

EPIDEMIOLOGYQ4

Abstract

Hemophiliacs are at a greater risk of contracting all kinds of hepatitis especially HEPATITIS C because of persistent consumption of blood products. Nowadays, an effective vaccine to prevent HEPATITIS C is not yet available and post transfusion transmission of this virus has remained as a problem. In this study we tried to survey the prevalence of HCV and its risk factors among a group of hemophilic patients in Iran.In a cross sectional study, we evaluated nearly all of hemophilic patients who referred to Iran HEMOPHILIA Society from 20 march 2000 to 20 march 2001. The seroprevalence of antibodies to HEPATITIS C (anti-HCV Ab) was studied with anti HCV enzyme linked immunosorbant assay (ELISA), and confirmed with recombinant immunoblot assay (RIBA). HBs Ag, HBs Ab and HIV antibody in the samples were detected as mentioned above. The study was performed on 176 HEMOPHILIAcs. Out of them, 106 patients (60.2%) were anti-HCV Ab positive. There is no significant relation between seropositivity for anti-HCV Ab and sex, age, marital status, type or the severity of bleeding disorder, type or number or duration of the product consumed and family history of hepatitis in our patients. Also, there is no significant relation between anti-HCV seropositivity and HBs Ag seropositivity in patients, but seroprevalence of anti-HCV Ab was significantly higher in HBs Ab positive patients compared with HBs Ab negatives (P=0.038). Four patients were HIV Ab positive, and all of them were positive for anti-HCV Ab, too.A high seroprevalence for anti-HCV Ab was detected in patients with HEMOPHILIA in our study. Whereas a number of effective strategies, including donor screening and especially viral inactivation procedures for concentrates and recently use of recombinant factor therapy, have been implemented in the world in order to prevent the transmission of viral infections due to blood or blood product transfusion. Surely the use of such strategies can reduce the prevalence of viral disease like viral hepatitis and AIDS in our HEMOPHILIAcs.

Cites

DETERMINATION OF HBS AB STABILITY AFTER HBV VACCINATION IN MULTITRANSFUSED PATIENTS, HAJAR HOSPITAL, SHAHREKORD, 2003

References

شیوع آنتی بادی علیه هپاتیت C در بیماران هموفیلی

Cite

APA: Copy

ALAVIAN, S.M., ARDESHIRI, A., & HAJARIZADEH, B.. (2003). PREVALENCE OF HCV, HBV AND HIV INFECTIONS AMONG HEMOPHILIACS. HAKIM RESEARCH JOURNAL, 6(2), 45-51. SID. https://sid.ir/paper/29232/en

Vancouver: Copy

ALAVIAN S.M., ARDESHIRI A., HAJARIZADEH B.. PREVALENCE OF HCV, HBV AND HIV INFECTIONS AMONG HEMOPHILIACS. HAKIM RESEARCH JOURNAL[Internet]. 2003;6(2):45-51. Available from: https://sid.ir/paper/29232/en

IEEE: Copy

S.M. ALAVIAN, A. ARDESHIRI, and B. HAJARIZADEH, “PREVALENCE OF HCV, HBV AND HIV INFECTIONS AMONG HEMOPHILIACS,” HAKIM RESEARCH JOURNAL, vol. 6, no. 2, pp. 45–51, 2003, [Online]. Available: https://sid.ir/paper/29232/en

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