PREVALENCE OF HEPATITIS B, C AND HIV IN HEMOPHILIAC PATIENTS OF EAST AZARBAIJAN IN 2004

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TORABI S.A.; ABEDASHTIANI K.; DEHKADA R.; MOGHADAM A.N.; BAHRAM M.KH.; BABAEI J.; TAHERI N.; DOULATKHAH ROUYA

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Journal: THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON) Year:2006 | Volume:2 | Issue:7 (Special Issue) Page(s): 291-299

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Title

PREVALENCE OF HEPATITIS B, C AND HIV IN HEMOPHILIAC PATIENTS OF EAST AZARBAIJAN IN 2004

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Keywords

HEMOPHILIAQ4

HEPATITIS CQ3

HEPATITIS BQ4

HIVQ4

Abstract

Background and ObjectivesDue to frequent tranfusion of blood components, HEMOPHILIAc patients have been exposed to a wide range of blood-borne viruses, among which the human immune deficiency virus (HIV) and the HEPATITIS C virus (HCV) have had a considerable impact on their life. Prior to the introduction of virus- inactivation methods in 1985, almost all treated HEMOPHILIAcs had been infected with HCV transmited by factor concentrates, and in most countries almost 50% of HEMOPHILIAcs had also been infected with HIV.Materials and Methods162 patients with inherited coagulation disorders including 113 HEMOPHILIA A and 17 HEMOPHILIA B patients living in East Azarbaijan participated in this observational study.The patients started to be tested for anti-HCV, anti-HIV, and HBs-Ag in 2003. Demographic information were gathered through questionnaires and some other information was taken from patient's medical records.ResultsAmong 113 HEMOPHILIA A and 17 HEMOPHILIA B patients, 63 (56%) and 9 (53%) were seropoitive for HCV-Ab respectively. The youngest patient who was seropositive for HCV-Ab was eleven years old, and his first blood tranfusion occurred in 1993. No child under the age of 10 was HCV positive; in other words, there was no case of HCV in 1995 (P<0.001). In HEMOPHILIA A group one patient (0.9%) was seropositive for HIV and 3 (2.7%) were seropositive for HBs-Ag. HCV status was also related to baseline factor activity level. In more severely affected patients of both group A and B (< 1% factor activity) , the prevalence of HCV was 75%. ConclusionsHEMOPHILIAc patients born after 1995 have no evidence of HIV infection. Only one patient (0.9%) was seropositive for HIV and in this respect our province as compared with other countries is in a good condition.

Cites

PREVALENCE OF HEPATITIS B, C AND HIV INFECTION IN THALASSEMIC AND HEMOPHILIC PATIENTS OF MARKAZI PROVINCE IN 2004

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APA: Copy

TORABI, S.A., ABEDASHTIANI, K., DEHKADA, R., MOGHADAM, A.N., BAHRAM, M.KH., BABAEI, J., TAHERI, N., & DOULATKHAH, ROUYA. (2006). PREVALENCE OF HEPATITIS B, C AND HIV IN HEMOPHILIAC PATIENTS OF EAST AZARBAIJAN IN 2004 . THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), 2(7 (Special Issue)), 291-299. SID. https://sid.ir/paper/78753/en

Vancouver: Copy

TORABI S.A., ABEDASHTIANI K., DEHKADA R., MOGHADAM A.N., BAHRAM M.KH., BABAEI J., TAHERI N., DOULATKHAH ROUYA. PREVALENCE OF HEPATITIS B, C AND HIV IN HEMOPHILIAC PATIENTS OF EAST AZARBAIJAN IN 2004 . THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON)[Internet]. 2006;2(7 (Special Issue)):291-299. Available from: https://sid.ir/paper/78753/en

IEEE: Copy

S.A. TORABI, K. ABEDASHTIANI, R. DEHKADA, A.N. MOGHADAM, M.KH. BAHRAM, J. BABAEI, N. TAHERI, and ROUYA DOULATKHAH, “PREVALENCE OF HEPATITIS B, C AND HIV IN HEMOPHILIAC PATIENTS OF EAST AZARBAIJAN IN 2004 ,” THE SCIENTIFIC JOURNAL OF IRANIAN BLOOD TRANSFUSION ORGANIZATION (KHOON), vol. 2, no. 7 (Special Issue), pp. 291–299, 2006, [Online]. Available: https://sid.ir/paper/78753/en

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