CYTOTOXIC PROPERTIES OF SOME MEDICINAL PLANT EXTRACTS FROM MAZANDARAN, IRAN

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NEMATI FARKHONDEH; DEHPOURI ABBAS ALI; ESLAMI BAHMAN; MAHDAVI VAHIDEH; MIRZANEJAD SEPIDEH

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Journal Paper

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Journal: Iranian Red Crescent Medical Journal Year:2013 | Volume:15 | Issue:11 Page(s): 0-0

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Title

CYTOTOXIC PROPERTIES OF SOME MEDICINAL PLANT EXTRACTS FROM MAZANDARAN, IRAN

Author(s)

Keywords

CYTOTOXINS

MEDICINAL PLANT

IRAN

Abstract

Background: It was shown that plants derived agents are being used for treatment of cancer. In this study, crude ethanolic extract of Consolida orientalis L., Ferula assa-foetida L., Coronilla varia L., Orobanche orientalis G. Beck were screened in vitro for cytotoxic activity on Hela (Human cervical carcinoma) cell line.Objectives: We performed the present study to evaluate the in vitro cytotoxic activity of four plant extracts that we gathered from north of IRAN, Mazandaran.Materials and Methods: Hela cells were treated with various concentrations of individual samples (0.0312, 0.0625, 0.125, 0.25, 0.5, 1, 2.5, 5, 7.5 and 10 mg/ml) for 72 hours. Cell proliferation measured by MTT assay.Results: Result from the performed assay showed that ethanolic extract of Consolida orientalis L., Ferula assa-foetida L., Coronilla varia L. has more significant cytotoxicity effect on Hela cell line than Orobanche orientalis G. Beck.Conclusions: Extracts of the Consolida orientalis L., Ferula assa-foetida L., Coronilla varia L. could be considered as potential sources of anticancer compounds but further studies are necessary for isolation and identification of biologically active substances.

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APA: Copy

NEMATI, FARKHONDEH, DEHPOURI, ABBAS ALI, ESLAMI, BAHMAN, MAHDAVI, VAHIDEH, & MIRZANEJAD, SEPIDEH. (2013). CYTOTOXIC PROPERTIES OF SOME MEDICINAL PLANT EXTRACTS FROM MAZANDARAN, IRAN. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 15(11), 0-0. SID. https://sid.ir/paper/292798/en

Vancouver: Copy

NEMATI FARKHONDEH, DEHPOURI ABBAS ALI, ESLAMI BAHMAN, MAHDAVI VAHIDEH, MIRZANEJAD SEPIDEH. CYTOTOXIC PROPERTIES OF SOME MEDICINAL PLANT EXTRACTS FROM MAZANDARAN, IRAN. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)[Internet]. 2013;15(11):0-0. Available from: https://sid.ir/paper/292798/en

IEEE: Copy

FARKHONDEH NEMATI, ABBAS ALI DEHPOURI, BAHMAN ESLAMI, VAHIDEH MAHDAVI, and SEPIDEH MIRZANEJAD, “CYTOTOXIC PROPERTIES OF SOME MEDICINAL PLANT EXTRACTS FROM MAZANDARAN, IRAN,” IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), vol. 15, no. 11, pp. 0–0, 2013, [Online]. Available: https://sid.ir/paper/292798/en

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