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Information Journal Paper

Title

THE PREVALENCE OF HEPATITIS B VIRUS INFECTION IN MASHHAD, IRAN: A POPULATION- BASED STUDY

Pages

  245-248

Abstract

 Background: HEPATITIS B VIRUS (HBV) infection is the most common and serious liver infection in the world. An estimated 350 million people are chronic carriers of this virus, of whom, more than 620,000 die from liver-related diseases annually. Due to the vaccination program, PREVALENCE of HBV, particularly among the younger generation, is reported to have declined in recent years in Iran.Objectives: The aim of this study was to evaluate the PREVALENCE of HBV infection in Mashhad, North-East of Iran.Patients and Methods: Three thousand one hundred and ninety eight (3198) individuals living in Mashhad were studied using cluster sampling method. HBV infection was determined by HBsAg ELISA commercial kit. Positive results were subjected for PCR using HBV-specific primers. HBeAg, HBeAb, and HBcAb-IgM ELISA tests were performed for HBsAg-positive samples.Results: Patients’ age ranged from 15 to 65 years (Mean=35.54±14.85). Thirty four (1.0%) of the subjects were positive for HBsAg, of whom, 2.9% (1 of 34 cases) were also positive in PCR-based screening. ELISA tests for HBeAg, HBeAb, and HBcAb IgM were positive in one (2.9%), 27 (79.4%) and one (2.9%) cases, respectively.Conclusions: According to our results, HBsAg was positive in 0.53 of the total population. The PREVALENCE of HBV infection was seemingly low in Mashhad; however, an upward trend was observed in older subjects probably due to successful HBV vaccination coverage in the younger generation. Continuous surveillance and periodic population-based studies are essential to monitor the PREVALENCE of HBV infection in Mashhad in the future.

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    APA: Copy

    SHAKERI, MOHAMMAD TAGHI, FOGHANIAN, BAHAREH, NOMANI, HOSEIN, GHAYOUR MOBARHAN, MAJID, NABAVINIA, MARYAM SADAT, ROSTAMI, SINA, AHADI, MITRA, & MESHKAT, ZAHRA. (2013). THE PREVALENCE OF HEPATITIS B VIRUS INFECTION IN MASHHAD, IRAN: A POPULATION- BASED STUDY. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 15(3), 245-248. SID. https://sid.ir/paper/292826/en

    Vancouver: Copy

    SHAKERI MOHAMMAD TAGHI, FOGHANIAN BAHAREH, NOMANI HOSEIN, GHAYOUR MOBARHAN MAJID, NABAVINIA MARYAM SADAT, ROSTAMI SINA, AHADI MITRA, MESHKAT ZAHRA. THE PREVALENCE OF HEPATITIS B VIRUS INFECTION IN MASHHAD, IRAN: A POPULATION- BASED STUDY. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)[Internet]. 2013;15(3):245-248. Available from: https://sid.ir/paper/292826/en

    IEEE: Copy

    MOHAMMAD TAGHI SHAKERI, BAHAREH FOGHANIAN, HOSEIN NOMANI, MAJID GHAYOUR MOBARHAN, MARYAM SADAT NABAVINIA, SINA ROSTAMI, MITRA AHADI, and ZAHRA MESHKAT, “THE PREVALENCE OF HEPATITIS B VIRUS INFECTION IN MASHHAD, IRAN: A POPULATION- BASED STUDY,” IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), vol. 15, no. 3, pp. 245–248, 2013, [Online]. Available: https://sid.ir/paper/292826/en

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