BARBERRY ADMINISTRATION AND PRO-OXIDANT–ANTIOXIDANT BALANCE IN PATIENTS WITH METABOLIC SYNDROME

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MOHAMMADI AKRAM; SAHEBKAR AMIRHOSSEIN; KERMANI TAYYEBEH; ZHILAEE MARZIEH; TAVALLAIEE SHIMA; GHAYOUR MOBARHAN MAJID

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Journal Paper

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Journal: Iranian Red Crescent Medical Journal Year:2014 | Volume:16 | Issue:12 Page(s): 0-0

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Title

BARBERRY ADMINISTRATION AND PRO-OXIDANT–ANTIOXIDANT BALANCE IN PATIENTS WITH METABOLIC SYNDROME

Author(s)

Keywords

METABOLIC CARDIOVASCULAR SYNDROME

BERBERIDACEAE

RANDOMIZED CONTROLLED TRIAL

Abstract

Background: Metabolic syndrome is the constellation of several cardiometabolic risk factors, and is associated with a heightened risk of coronary heart disease (CHD). The pro-oxidant–antioxidant balance (PAB) is a measure of factors that promote and control oxidative stress. PAB may also be associated with the risk factors of CHD.Objectives: This study aimed to explore the impact of supplementation with barberry, a fruit rich in antioxidants, on PAB in patients with metabolic syndrome.Patients and Methods: A total of 106 patients diagnosed with metabolic syndrome were randomized in two groups: case and control. The case group received three capsules of barberry and the control group received three capsules of placebo for 6 weeks. Serum PAB was measured in all patients before and after the intervention.Results: There was no significant difference between the groups regarding their baseline PAB values (P=0.32). A significant decrease in PAB was observed in the barberry group (P=0.022), whilst there was no significant change in the control group (P=0.18). The magnitude of change in PAB during the study was significantly greater in the case group compared to the control group (P=0.01).Conclusions: Barberry supplementation reduces oxidative burden in patients with metabolic syndrome.

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APA: Copy

MOHAMMADI, AKRAM, SAHEBKAR, AMIRHOSSEIN, KERMANI, TAYYEBEH, ZHILAEE, MARZIEH, TAVALLAIEE, SHIMA, & GHAYOUR MOBARHAN, MAJID. (2014). BARBERRY ADMINISTRATION AND PRO-OXIDANT–ANTIOXIDANT BALANCE IN PATIENTS WITH METABOLIC SYNDROME. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 16(12), 0-0. SID. https://sid.ir/paper/293030/en

Vancouver: Copy

MOHAMMADI AKRAM, SAHEBKAR AMIRHOSSEIN, KERMANI TAYYEBEH, ZHILAEE MARZIEH, TAVALLAIEE SHIMA, GHAYOUR MOBARHAN MAJID. BARBERRY ADMINISTRATION AND PRO-OXIDANT–ANTIOXIDANT BALANCE IN PATIENTS WITH METABOLIC SYNDROME. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)[Internet]. 2014;16(12):0-0. Available from: https://sid.ir/paper/293030/en

IEEE: Copy

AKRAM MOHAMMADI, AMIRHOSSEIN SAHEBKAR, TAYYEBEH KERMANI, MARZIEH ZHILAEE, SHIMA TAVALLAIEE, and MAJID GHAYOUR MOBARHAN, “BARBERRY ADMINISTRATION AND PRO-OXIDANT–ANTIOXIDANT BALANCE IN PATIENTS WITH METABOLIC SYNDROME,” IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), vol. 16, no. 12, pp. 0–0, 2014, [Online]. Available: https://sid.ir/paper/293030/en

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