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Information Journal Paper

Title

LONG-TERM EXPOSURE OF LEAD ACETATE ON RABBIT RENAL TISSUE

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  0-0

Abstract

 Background: Lead has been widely used in different industries for ages. It is one of the heavy metals, highly poisonous even at low doses, and has biochemical, physiological and behavioral side effects on human and animals. It has been shown that lead has toxic effects on different tissues such as neural and genitourinary tissues, cardiovascular systems and blood. Therefore, high attention has been paid to its environmental pollutions.Objectives: Although many histological and biochemical studies have reported about the effects of lead on the renal tissue, there are a few studies about the ultrastructure and MORPHOMETRIC effects of lead on the KIDNEY. Hence, the aim of this study was the evaluation of morphology and MORPHOMETRICs of rabbit renal URINARY BARRIER ultrastructure following long-term exposure to LEAD ACETATE.Materials and Methods: In this experimental study, 20 male New Zealand rabbits were divided into control and test groups (10 in each). The test group was injected intraperitoneally with chronic dose (8.5 mg/kg of body weight) of LEAD ACETATE and for the control group the same volume of normal saline was used, every other day for 10 weeks. After anesthetizing, the biopsies of renal tissues were taken for light and electron microscopic MORPHOMETRIC and MORPHOLOGIC analyses.Results: Long-term exposure to LEAD ACETATE caused histopathology effects including dilatation, congestion, nuclei heterochromatic effects, increase in diameter of renal tubules and URINARY BARRIER thickness in rabbit renal tissue.Conclusions: Quantitative and qualitative results of long-term LEAD ACETATE exposure showed many histopathology side-effects, especially in the URINARY BARRIER.

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    APA: Copy

    KARIMFAR, MOHAMMAD HASSAN, BARGAHI, AFSHAR, MOSHTAGHI, DARAB, & FARZADINIA, PARVIZ. (2016). LONG-TERM EXPOSURE OF LEAD ACETATE ON RABBIT RENAL TISSUE. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 18(2), 0-0. SID. https://sid.ir/paper/293416/en

    Vancouver: Copy

    KARIMFAR MOHAMMAD HASSAN, BARGAHI AFSHAR, MOSHTAGHI DARAB, FARZADINIA PARVIZ. LONG-TERM EXPOSURE OF LEAD ACETATE ON RABBIT RENAL TISSUE. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)[Internet]. 2016;18(2):0-0. Available from: https://sid.ir/paper/293416/en

    IEEE: Copy

    MOHAMMAD HASSAN KARIMFAR, AFSHAR BARGAHI, DARAB MOSHTAGHI, and PARVIZ FARZADINIA, “LONG-TERM EXPOSURE OF LEAD ACETATE ON RABBIT RENAL TISSUE,” IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), vol. 18, no. 2, pp. 0–0, 2016, [Online]. Available: https://sid.ir/paper/293416/en

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