ANTISHIVERING EFFECT OF DEXMEDETOMIDINE ON PATIENTS UNDERGOING VIDEO-ASSISTED THORACOSCOPIC WEDGE RESECTION

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JO YOUN YI; LEE KYUNG CHEON; PARK HEE YEON; KIM JU HO; LEE JI YEON

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Journal: Iranian Red Crescent Medical Journal Year:2018 | Volume:20 | Issue:3 Page(s): 0-0

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Title

ANTISHIVERING EFFECT OF DEXMEDETOMIDINE ON PATIENTS UNDERGOING VIDEO-ASSISTED THORACOSCOPIC WEDGE RESECTION

Author(s)

Keywords

ANESTHESIA

DEXMEDETOMIDINE

GENERAL

SHIVERING

VIDEO-ASSISTED THORACOSCOPIC SURGERY

Abstract

Background: Post-anesthetic SHIVERING can cause post- surgical pain or discomfort, and create oxygen supply/demand imbalance.Objectives: The current study aimed at evaluating the effects of DEXMEDETOMIDINE on the incidence and intensity of SHIVERING and core temperature after GENERAL ANESTHESIA.Methods: The current randomized, double-blind, placebo-controlled, clinical trial was conducted at a single center (Gil Medical Center, Incheon, South Korea) from January to December 2016 with convenience sampling and simple random allocation. A total of 40 patients undergoing video-assisted thoracoscopic (VATS) wedge resection were randomly assigned to receive either 1mg/kg of DEXMEDETOMIDINE (Dexmedetomidine group, n=20) or normal saline (control group, n=20) 10 minutes after skin incision. Hemodynamic variables and esophageal and tympanic temperatures were recorded five minutes after anesthetic induction, five minutes after achieving a lateral position, every five minutes after carbon dioxide insufflation to the thoracic cavity, and at the end of surgery. Incidences and intensities of post-anesthetic SHIVERING, and postoperative pain scores were recorded.Results: Median postoperative pain score was significantly lower in the DEXMEDETOMIDINE group than the control group (4 (0-5) vs.5 (3.25-6) (median (interquartile range)), P=0.004). In the post-anesthetic care unit (PACU), the incidence of SHIVERING was significantly lower in the DEXMEDETOMIDINE group than in the control group (0/20 (0%) vs.6/20 (30%), P=0.020); but the incidence of hypothermia was higher in the DEXMEDETOMIDINE group than in the control group (6/20 (30%) vs.0/20 (0%), P=0.020).Conclusions: A single intraoperative dose of DEXMEDETOMIDINE (1 mg/kg) may reduce postoperative SHIVERING and pain scores, but it might also increase the incidence of postoperative hypothermia in patients undergoing Sevoflurane ANESTHESIA for video-assisted thoracoscopic wedge resection.

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APA: Copy

JO, YOUN YI, LEE, KYUNG CHEON, PARK, HEE YEON, KIM, JU HO, & LEE, JI YEON. (2018). ANTISHIVERING EFFECT OF DEXMEDETOMIDINE ON PATIENTS UNDERGOING VIDEO-ASSISTED THORACOSCOPIC WEDGE RESECTION. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 20(3), 0-0. SID. https://sid.ir/paper/293710/en

Vancouver: Copy

JO YOUN YI, LEE KYUNG CHEON, PARK HEE YEON, KIM JU HO, LEE JI YEON. ANTISHIVERING EFFECT OF DEXMEDETOMIDINE ON PATIENTS UNDERGOING VIDEO-ASSISTED THORACOSCOPIC WEDGE RESECTION. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)[Internet]. 2018;20(3):0-0. Available from: https://sid.ir/paper/293710/en

IEEE: Copy

YOUN YI JO, KYUNG CHEON LEE, HEE YEON PARK, JU HO KIM, and JI YEON LEE, “ANTISHIVERING EFFECT OF DEXMEDETOMIDINE ON PATIENTS UNDERGOING VIDEO-ASSISTED THORACOSCOPIC WEDGE RESECTION,” IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), vol. 20, no. 3, pp. 0–0, 2018, [Online]. Available: https://sid.ir/paper/293710/en

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