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Information Journal Paper

Title

CELERY PLUS ANISE VERSUS METFORMIN FOR TREATMENT OF OLIGOMENORRHEAIN POLYCYSTIC OVARY SYNDROME: A TRIPLE-BLIND, RANDOMIZED CLINICALTRIAL

Pages

  0-0

Abstract

 Background: POLYCYSTIC OVARY SYNDROME (PCOS)-induced OLIGOMENORRHEA can leave psychological and non-psychological impactson women. Among the proposed strategies for its treatment, herbal medications are of importance due to favorable effect profiles. Objectives: We planned a study to compare the effects of Celery and Anise combination (CAC) and METFORMIN (met. ) on OLIGOMENORRHEAin PCOS patients. Methods: We conducted a triple-blind, Randomized clinical trial on 72 patients that were randomly allocated into two equal groupsto receive six capsules of either CAC (750mgeach) or met. (250mgeach) at three separate doses for 15 days beginning from the follicularphase. If the bleeding occurred, three capsules of either placebo or met. would be administered daily during the menstruationphase, and then the follicular phase step with six capsules would be repeated. If the bleeding did not occur, three capsules of eitherplacebo or met. would be administered each day for 15 days. The regularity of menstrual bleeding as the primary outcome, as wellas testosterone, luteinizing hormone/follicular stimulating hormone ratio (LH/FSH), and complications, was assessed before andafter the three cycles. Results: The mean age standard deviation of patients was 26. 5 6. 1. The mean Body Mass Index was 26. 4 3. 5. CAC significantlyimproved OLIGOMENORRHEA (58. 3% vs. 25%, P < 0. 01), increased bleeding episodes (P = 0. 003), and reduced testosterone (mean difference: 0. 16 vs.-0. 02, P = 0. 005) and LH/FSH (mean difference: 0. 75 vs.-0. 08, P = 0. 002) without any major side effects compared tomet. Conclusions: We showed that Celery and Anise combination could regulate menstrual cycles and improve OLIGOMENORRHEA in polycysticovary syndrome patients superiorly to METFORMIN.

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    APA: Copy

    Moini Jazani, Arezoo, NAZEMIYEH, HOSSEIN, TANSAZ, MOJGAN, SADEGHI BAZARGANI, HOMAYOUN, FAZLJOU, SEYED MOHAMMAD BAGHER, Nasimi Doost Azgomi, Ramin, & HAMDI, KOBRA. (2018). CELERY PLUS ANISE VERSUS METFORMIN FOR TREATMENT OF OLIGOMENORRHEAIN POLYCYSTIC OVARY SYNDROME: A TRIPLE-BLIND, RANDOMIZED CLINICALTRIAL. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 20(5), 0-0. SID. https://sid.ir/paper/293743/en

    Vancouver: Copy

    Moini Jazani Arezoo, NAZEMIYEH HOSSEIN, TANSAZ MOJGAN, SADEGHI BAZARGANI HOMAYOUN, FAZLJOU SEYED MOHAMMAD BAGHER, Nasimi Doost Azgomi Ramin, HAMDI KOBRA. CELERY PLUS ANISE VERSUS METFORMIN FOR TREATMENT OF OLIGOMENORRHEAIN POLYCYSTIC OVARY SYNDROME: A TRIPLE-BLIND, RANDOMIZED CLINICALTRIAL. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)[Internet]. 2018;20(5):0-0. Available from: https://sid.ir/paper/293743/en

    IEEE: Copy

    Arezoo Moini Jazani, HOSSEIN NAZEMIYEH, MOJGAN TANSAZ, HOMAYOUN SADEGHI BAZARGANI, SEYED MOHAMMAD BAGHER FAZLJOU, Ramin Nasimi Doost Azgomi, and KOBRA HAMDI, “CELERY PLUS ANISE VERSUS METFORMIN FOR TREATMENT OF OLIGOMENORRHEAIN POLYCYSTIC OVARY SYNDROME: A TRIPLE-BLIND, RANDOMIZED CLINICALTRIAL,” IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), vol. 20, no. 5, pp. 0–0, 2018, [Online]. Available: https://sid.ir/paper/293743/en

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