COMPARISON OF HIGH-SENSITIVE CARDIAC TROPONIN-T CHANGES BETWEENNON-ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION AND NON-CORONARYARTERY PATIENTS

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AHMADI ALI AKBAR; ALEMZADEH ANSARI MOHAMMAD JAVAD; JENAB YASER; GHAFFARI MARANDI NEDA

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Journal: Iranian Red Crescent Medical Journal Year:2017 | Volume:19 | Issue:10 Page(s): 0-0

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Title

COMPARISON OF HIGH-SENSITIVE CARDIAC TROPONIN-T CHANGES BETWEENNON-ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION AND NON-CORONARYARTERY PATIENTS

Author(s)

AHMADI ALI AKBAR | ALEMZADEH ANSARI MOHAMMAD JAVAD | JENAB YASER | GHAFFARI MARANDI NEDA | Issue Writer Certificate

Keywords

ACUTE CORONARY SYNDROME

MYOCARDIAL INFARCTION

TROPONIN T

Abstract

Background: In the absence of ACUTE CORONARY SYNDROME (ACS), various conditions may increase the level of cardiac troponins. Objectives: We aimed to determine the absolute and relative changes of high-sensitive cardiac TROPONIN T (hs-cTnT) in 2 groups ofpatients: non-ST-segment-elevation MYOCARDIAL INFARCTION (NSTEMI) and non-ACS patients. Methods: In this longitudinal study, performed between December 2011 and July 2012, we calculated the absolute and relativechanges of hs-cTnT and troponin velocity in consecutive patients, admitted to the emergency department of Tehran Heart Center. The patients had symptoms of acute MI with elevated baseline hs-cTnT levels. Blood sampling was performed 3 times followingadmission. The hs-cTnT changes were evaluated and compared between the 2 groups of NSTEMI and non-ACS patients. Results: After exclusion, the second and third samples (taken 12 and 36 hours after admission on average, respectively) were availablein 889 and 641 patients, respectively. Cardiovascular risk factors, including hyperlipidemia, diabetes mellitus, smoking, andhistory of coronary events or intervention, were significantly more frequent in the NSTEMI group, compared to the non-ACS group. The hs-cTnT level at baseline and in the subsequent samples was significantly higher in the NSTEMI group, compared to the non-ACSgroup. Also, the absolute and relative changes in hs-cTnT were more significant in the NSTEMI group. Moreover, hs-cTnT velocitywithin the first 12 hours was significantly higher in the NSTEMI group, compared to the non-ACS group (18. 85 84. 89 ng/L/h vs. 4. 96 14. 58 ng/L/h; P < 0. 001). Conclusions: The changes in hs-cTnT (ie, absolute, relative, and velocity changes) were more significant in the NSTEMI group incomparison with non-ACS patients.

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References

EVALUATION OF CARDIAC BIOMARKERS AFTER PERCUTANEOUS BALLOON MITRAL COMMISSUROTOMY (CASE REPORT)

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APA: Copy

AHMADI, ALI AKBAR, ALEMZADEH ANSARI, MOHAMMAD JAVAD, JENAB, YASER, & GHAFFARI MARANDI, NEDA. (2017). COMPARISON OF HIGH-SENSITIVE CARDIAC TROPONIN-T CHANGES BETWEENNON-ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION AND NON-CORONARYARTERY PATIENTS. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 19(10), 0-0. SID. https://sid.ir/paper/293766/en

Vancouver: Copy

AHMADI ALI AKBAR, ALEMZADEH ANSARI MOHAMMAD JAVAD, JENAB YASER, GHAFFARI MARANDI NEDA. COMPARISON OF HIGH-SENSITIVE CARDIAC TROPONIN-T CHANGES BETWEENNON-ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION AND NON-CORONARYARTERY PATIENTS. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)[Internet]. 2017;19(10):0-0. Available from: https://sid.ir/paper/293766/en

IEEE: Copy

ALI AKBAR AHMADI, MOHAMMAD JAVAD ALEMZADEH ANSARI, YASER JENAB, and NEDA GHAFFARI MARANDI, “COMPARISON OF HIGH-SENSITIVE CARDIAC TROPONIN-T CHANGES BETWEENNON-ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION AND NON-CORONARYARTERY PATIENTS,” IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), vol. 19, no. 10, pp. 0–0, 2017, [Online]. Available: https://sid.ir/paper/293766/en

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