THE EFFECT OF ARTERIAL O2 SATURATIONAND HEARTRATE ON BLOOD PRESSURE DURING HYPOXIA

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BOSKABADI M.H.; KARBANDI S.; ABEDINZADEH A.

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Journal Paper

Paper Information

Journal: Medical Journal of The Islamic Republic of Iran Year:2000 | Volume:14 | Issue:1 Page(s): 37-41

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Information Journal Paper

Title

THE EFFECT OF ARTERIAL O2 SATURATIONAND HEARTRATE ON BLOOD PRESSURE DURING HYPOXIA

Author(s)

BOSKABADI M.H. | KARBANDI S. | ABEDINZADEH A. | Issue Writer Certificate

Keywords

BLOOD PRESSURE

HEART RATE

O2 SATURATION

HYPOXIA

Abstract

A periodic increase in BLOOD PRESSURE (BP) occurs during apneic episodes in patients with obstructive sleep apnea (OSA). Several factors including hypoxemia and an increase in HEART RATE (HR) were reponed to be responsible for this increased BP.To examine the contribution of these two factors in increasing BP, 35 healthy male subjects (mean age±SD=23.64±3.80) were studied in three experimental conditions, each condition for two minutes, including; breathing room air at rest (nonnoxic), breathing low O2 (10%) air (hypoxic), and exercising on an ergometer while breathing room air (exercise). During the last minutes of each condition, changes in mean BP (DmBP), HR (DHR), and arterial O2 saturation (DSaO2) were measured.The results showed that DmBP and DHR were significantly higher in both hypoxic and exercise conditions than nonnoxic condition (p<0.001) for both cases). However, DSaO2 was significantly lower in the hypoxic state compared to nonnoxic conditions. There was no significant difference in DHR between hypoxic and exercise groups, but both DmBP and DSaO2 were significantly lower in hypoxic than exercise conditions (p<0.005 and p<0.001 for for DmBP and DSaO2 , respectively). There was a weak correlation between DmBP and DHR in the hypoxic condition (r=0.3, p<0.05), but the correlation between DmBP and DHR in the exercise condition was stronger (r=0.57, p<0.001).These results indicated that although hypoxemia contributes to increased BP during HYPOXIA, an increase in HR is a stronger mechanism for this phenomenon.

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APA: Copy

BOSKABADI, M.H., KARBANDI, S., & ABEDINZADEH, A.. (2000). THE EFFECT OF ARTERIAL O₂ SATURATIONAND HEARTRATE ON BLOOD PRESSURE DURING HYPOXIA. MEDICAL JOURNAL OF THE ISLAMIC REPUBLIC OF IRAN (MJIRI), 14(1), 37-41. SID. https://sid.ir/paper/294305/en

Vancouver: Copy

BOSKABADI M.H., KARBANDI S., ABEDINZADEH A.. THE EFFECT OF ARTERIAL O₂ SATURATIONAND HEARTRATE ON BLOOD PRESSURE DURING HYPOXIA. MEDICAL JOURNAL OF THE ISLAMIC REPUBLIC OF IRAN (MJIRI)[Internet]. 2000;14(1):37-41. Available from: https://sid.ir/paper/294305/en

IEEE: Copy

M.H. BOSKABADI, S. KARBANDI, and A. ABEDINZADEH, “THE EFFECT OF ARTERIAL O₂ SATURATIONAND HEARTRATE ON BLOOD PRESSURE DURING HYPOXIA,” MEDICAL JOURNAL OF THE ISLAMIC REPUBLIC OF IRAN (MJIRI), vol. 14, no. 1, pp. 37–41, 2000, [Online]. Available: https://sid.ir/paper/294305/en

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