ASSOCIATION STUDY BETWEEN SCHIZOPHRENIA AND THE DISC1 GENE POLYMORPHISM

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

FOROUGHMAND ALI MOHAMMAD; HAIDARI MARYAM; GALEHDARI HAMID; POORYASIN ATEFEH; KAZEMINEJAD SEYED REZA; HOSSEINI SHIVA; KHAJEH MOGEHI NAHID

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Medical Journal of The Islamic Republic of Iran Year:2010 | Volume:24 | Issue:1 Page(s): 29-34

Download Full-Text

View:

355

Download:

113

Cites:

Information Journal Paper

Title

ASSOCIATION STUDY BETWEEN SCHIZOPHRENIA AND THE DISC1 GENE POLYMORPHISM

Author(s)

Keywords

ASSOCIATION STUDY

SCHIZOPHRENIA

DISC1 GENE

RS821616

SINGLE NUCLEOTIDE POLYMORPHISM

Abstract

Background: The disrupted-in-schizophrenia 1 (DISC1) gene, on the chromosome position 1q42, was initially identified at the breakpoint of a balanced translocation, t (1, 11) (q42.1; q14.3), which segregated with major mental disorders in a large Scottish family.Methods: Our samples included 200 unrelated patients diagnosed with SCHIZOPHRENIA on the basis of DSM-IV criteria and 200 normal controls, which were gathered from Iran. The allele and genotype frequencies of the polymorphism were determined using Polymerase Chain Reaction-Restricted Fragment Length Polymorphism (PCR-RFLP) and the data were analyzed by Logistic Regression test.Results: In this study we genotyped the RS821616 polymorphism (Serin704Cystein) located within exon 11 of the DISC1 GENE. The samples were matched on the basis of sex and ethnicity. We used the case control study to determine the possible association between the ser704cys (rs821616) polymorphism and SCHIZOPHRENIA. Analysis of data in the samples, revealed no association between the RS821616 polymorphism and SCHIZOPHRENIA (OR=0.697, 95% CI=0.47-1.033, P=0.072).Conclusion: In this study we did not find any association between the RS821616 SNPand SCHIZOPHRENIA.

Cites

No record.

References

No record.

Cite

APA: Copy

FOROUGHMAND, ALI MOHAMMAD, HAIDARI, MARYAM, GALEHDARI, HAMID, POORYASIN, ATEFEH, KAZEMINEJAD, SEYED REZA, HOSSEINI, SHIVA, & KHAJEH MOGEHI, NAHID. (2010). ASSOCIATION STUDY BETWEEN SCHIZOPHRENIA AND THE DISC1 GENE POLYMORPHISM. MEDICAL JOURNAL OF THE ISLAMIC REPUBLIC OF IRAN (MJIRI), 24(1), 29-34. SID. https://sid.ir/paper/294385/en

Vancouver: Copy

FOROUGHMAND ALI MOHAMMAD, HAIDARI MARYAM, GALEHDARI HAMID, POORYASIN ATEFEH, KAZEMINEJAD SEYED REZA, HOSSEINI SHIVA, KHAJEH MOGEHI NAHID. ASSOCIATION STUDY BETWEEN SCHIZOPHRENIA AND THE DISC1 GENE POLYMORPHISM. MEDICAL JOURNAL OF THE ISLAMIC REPUBLIC OF IRAN (MJIRI)[Internet]. 2010;24(1):29-34. Available from: https://sid.ir/paper/294385/en

IEEE: Copy

ALI MOHAMMAD FOROUGHMAND, MARYAM HAIDARI, HAMID GALEHDARI, ATEFEH POORYASIN, SEYED REZA KAZEMINEJAD, SHIVA HOSSEINI, and NAHID KHAJEH MOGEHI, “ASSOCIATION STUDY BETWEEN SCHIZOPHRENIA AND THE DISC1 GENE POLYMORPHISM,” MEDICAL JOURNAL OF THE ISLAMIC REPUBLIC OF IRAN (MJIRI), vol. 24, no. 1, pp. 29–34, 2010, [Online]. Available: https://sid.ir/paper/294385/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops