COMPARING THE LEVELS OF BHCG, PROGESTERONE AND ESTRADIOL BETWEEN ECTOPIC PREGNANCY AND NORMAL INTRAUTERINE PREGNANCY

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GHARA BAGHI P.; ABD ELAHIFARD S.; GHARABAGHI MANIZHEH; NOURI MOHAMMAD

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Journal: International Journal of Reproductive BioMedicine Year:2007 | Volume:5 | Issue:4 Page(s): 187-190

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Title

COMPARING THE LEVELS OF BHCG, PROGESTERONE AND ESTRADIOL BETWEEN ECTOPIC PREGNANCY AND NORMAL INTRAUTERINE PREGNANCY

Author(s)

GHARA BAGHI P. | ABD ELAHIFARD S. | GHARABAGHI MANIZHEH | NOURI MOHAMMAD | Issue Writer Certificate

Keywords

BETA SUBUNIT OF HUMAN CHORIONIC GONADOTROPIN (BHCG)

ESTRADIOL

PROGESTERONE

ECTOPIC PREGNANCY

NORMAL INTRAUTERINE PREGNANCY

Abstract

Background: The value of serial measurement of serum b subunit of human chorionic gonadotropin (bHCG) and ultrasonography in the early diagnosis of ECTOPIC PREGNANCY has well established.Objective: The objective of this study was to explore the diagnostic value of raising level of serum bHCG, single measurement of PROGESTERONE (P) and estradiol (E2) in early diagnosis of ECTOPIC PREGNANCY.Materials and Methods: Serum levels of bHCG and estradiol were measured by Radio Immuno Sorbent Assay (RIA) and PROGESTERONE level was measured by Enzyme Linked Immuno Sorbent Assay (ELISA) techniques in 43 symptomatic women with ECTOPIC PREGNANCY and 42 women with NORMAL INTRAUTERINE PREGNANCY in Alzahra Hospital, Tabriz, Iran. These values were compared by T-test. By determining cut-off levels of these parameters the efficiency and sensitivity of them in prediction of ECTOPIC PREGNANCY was estimated.Results: The mean serum levels of bHCG, estradiol and PROGESTERONE in patients with ectopic pregnancies (940±552 mlu/ml, 593±237 pg/ml, 5.83±3.41 ng/ml, respectively) were significantly lower than these levels in normal intrauterine pregnancies (4620±2030 mlu/ml, 1627±435 pg/ml, 24.8±6.08 ng/ml, respectively). The average rate of bHCG rising was 8.2% for 24 hours in patients with ECTOPIC PREGNANCY (EP) and 32.8% in normal intrauterine pregnancies (NIUP).Conclusions In this study single measurement of serum PROGESTERONE level has the greatest sensitivity (100%) and specificity (98%) in the diagnosis of ECTOPIC PREGNANCY.

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APA: Copy

GHARA BAGHI, P., ABD ELAHIFARD, S., GHARABAGHI, MANIZHEH, & NOURI, MOHAMMAD. (2007). COMPARING THE LEVELS OF BHCG, PROGESTERONE AND ESTRADIOL BETWEEN ECTOPIC PREGNANCY AND NORMAL INTRAUTERINE PREGNANCY. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 5(4), 187-190. SID. https://sid.ir/paper/295135/en

Vancouver: Copy

GHARA BAGHI P., ABD ELAHIFARD S., GHARABAGHI MANIZHEH, NOURI MOHAMMAD. COMPARING THE LEVELS OF BHCG, PROGESTERONE AND ESTRADIOL BETWEEN ECTOPIC PREGNANCY AND NORMAL INTRAUTERINE PREGNANCY. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2007;5(4):187-190. Available from: https://sid.ir/paper/295135/en

IEEE: Copy

P. GHARA BAGHI, S. ABD ELAHIFARD, MANIZHEH GHARABAGHI, and MOHAMMAD NOURI, “COMPARING THE LEVELS OF BHCG, PROGESTERONE AND ESTRADIOL BETWEEN ECTOPIC PREGNANCY AND NORMAL INTRAUTERINE PREGNANCY,” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 5, no. 4, pp. 187–190, 2007, [Online]. Available: https://sid.ir/paper/295135/en

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