IMMUNOHISTOCHEMICAL LOCALIZATION OF ENDOTHELIAL NITRIC OXIDE SYNTHASE IN ENDOMETRIAL TISSUE OF WOMEN WITH UNEXPLAINED INFERTILITY

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

NAJAFI TOHID; GHAFFARI NOVIN MAREFAT; PAKRAVESH JALIL; FOGHI KHADIJEH; FADAYI FATEMEH; RAHIMI GELAREH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: International Journal of Reproductive BioMedicine Year:2012 | Volume:10 | Issue:2 Page(s): 121-126

Download Full-Text

View:

336

Download:

106

Cites:

Information Journal Paper

Title

IMMUNOHISTOCHEMICAL LOCALIZATION OF ENDOTHELIAL NITRIC OXIDE SYNTHASE IN ENDOMETRIAL TISSUE OF WOMEN WITH UNEXPLAINED INFERTILITY

Author(s)

Keywords

UNEXPLAINED INFERTILITY

ENOS

IMMUNOHISTOCHEMISTRY

HUMAN ENDOMETRIUM

Abstract

Background: Nitric oxide (NO) is a molecule that incorporates in many physiological processes of female reproductive system. Recent studies suggested the possible role of endothelial isoform of nitric oxide synthase (eNOS) enzyme in female infertility.Objective: The aim of this study is to evaluate the expression of endothelial nitric oxide synthase in endometrial tissue of women with UNEXPLAINED INFERTILITY.Materials and Methods: In this case-control study a total of 18 endometrial tissues obtained from 10 women with UNEXPLAINED INFERTILITY and 8 normal and fertile women by endometrial biopsy, 6 to 10 days after LH surge. Specimens were fixed in 4% paraformaldhyde fixative and frozen sectioned for semi-quantitative immunohistochemical evaluation using monoclonal anti-human ENOS antibody. Hematoxilin and Eosin was used for Histological dating.Results: Localization of endothelial nitric oxide synthase was seen in glandular and luminal epithelium, vascular endothelium and stroma in both fertile women and women with UNEXPLAINED INFERTILITY. Although there were differences in immunoreactivity of glandular epithelium (p=0.44), vascular endothelium (p=0.60) and stroma (p=0.63) but only over-expression of ENOS in luminal epithelium (p=0.045) of women with UNEXPLAINED INFERTILITY compared to fertile women was statistically significant (p<0.05).Conclusion: This study suggests that changes in luminal expression of ENOS may influence receptivity of endometrium.

Cites

No record.

References

No record.

Cite

APA: Copy

NAJAFI, TOHID, GHAFFARI NOVIN, MAREFAT, PAKRAVESH, JALIL, FOGHI, KHADIJEH, FADAYI, FATEMEH, & RAHIMI, GELAREH. (2012). IMMUNOHISTOCHEMICAL LOCALIZATION OF ENDOTHELIAL NITRIC OXIDE SYNTHASE IN ENDOMETRIAL TISSUE OF WOMEN WITH UNEXPLAINED INFERTILITY. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 10(2), 121-126. SID. https://sid.ir/paper/295869/en

Vancouver: Copy

NAJAFI TOHID, GHAFFARI NOVIN MAREFAT, PAKRAVESH JALIL, FOGHI KHADIJEH, FADAYI FATEMEH, RAHIMI GELAREH. IMMUNOHISTOCHEMICAL LOCALIZATION OF ENDOTHELIAL NITRIC OXIDE SYNTHASE IN ENDOMETRIAL TISSUE OF WOMEN WITH UNEXPLAINED INFERTILITY. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2012;10(2):121-126. Available from: https://sid.ir/paper/295869/en

IEEE: Copy

TOHID NAJAFI, MAREFAT GHAFFARI NOVIN, JALIL PAKRAVESH, KHADIJEH FOGHI, FATEMEH FADAYI, and GELAREH RAHIMI, “IMMUNOHISTOCHEMICAL LOCALIZATION OF ENDOTHELIAL NITRIC OXIDE SYNTHASE IN ENDOMETRIAL TISSUE OF WOMEN WITH UNEXPLAINED INFERTILITY,” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 10, no. 2, pp. 121–126, 2012, [Online]. Available: https://sid.ir/paper/295869/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops