ASSESSING THE EFFICACY OF ASPIRATION AND ETHANOL INJECTION IN RECURRENT ENDOMETRIOMA BEFORE IVF CYCLE: A RANDOMIZED CLINICAL TRIAL

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AFLATOONIAN ABASS; RAHMANI ELHAM; RAHSEPAR MOZHGAN

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Journal Paper

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Journal: International Journal of Reproductive BioMedicine Year:2013 | Volume:11 | Issue:3 Page(s): 179-184

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Title

ASSESSING THE EFFICACY OF ASPIRATION AND ETHANOL INJECTION IN RECURRENT ENDOMETRIOMA BEFORE IVF CYCLE: A RANDOMIZED CLINICAL TRIAL

Author(s)

AFLATOONIAN ABASS | RAHMANI ELHAM | RAHSEPAR MOZHGAN | Issue Writer Certificate

Keywords

ENDOMETRIOMA

ETHANOL SCLEROTHERAPY

FERTILIZATION IN-VITRO

Abstract

Background: Endometriosis is a common hormone-dependent gynecologic disease with a high recurrence. Laparotomy or laparoscopy is the standard surgery for the large ENDOMETRIOMA. Also, sclerotherapy is basically used to treat different diseases one of which is ENDOMETRIOMA.Objective: The study was designed to assess the value of transvaginal ultrasound-guided ETHANOL SCLEROTHERAPY in patients with a recurrent ENDOMETRIOMA.Materials and Methods: In a randomized clinical trial, an interventional group of 20 patients underwent transvaginal ETHANOL SCLEROTHERAPY for recurrent ovarian ENDOMETRIOMA. The patients were followed up first after one and two weeks and then after one, two, and three months. If the patients had no ENDOMETRIOMA, they were treated with in vitro fertilization (IVF) (standard long protocol). A control group of 20 patients with ENDOMETRIOMA were enrolled for an IVF protocol. They had no treatment by ETHANOL SCLEROTHERAPY. IVF parameters, pregnancy rates, and implantation rates were compared in both groups.Results: The demographic data showed no difference between the two groups. The initial mean endometria size was 41.45±15.9 cm, the recurrence rate after 6 months was 4 (20%), FSH before and after sclerotherapy was 6.97±2.25 IU/L and 6.78±1.88 IU/L (p=0.343). The clinical pregnancy rate was 6 (33.3%) vs. 3 (15%), (p=0.616). The fertilization rate emerged 63.06% in study group vs. 60.38%, (p=0.57). The implantation rate turned out 12.9% in study group vs. 7.5%, (p=0.52). None of these results were significant. However, the data pointed to a better trend toward the ETHANOL SCLEROTHERAPY group. Conclusion: ETHANOL SCLEROTHERAPY could be an effective strategy for the treatment of recurrent ENDOMETRIOMA especially before IVF.

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APA: Copy

AFLATOONIAN, ABASS, RAHMANI, ELHAM, & RAHSEPAR, MOZHGAN. (2013). ASSESSING THE EFFICACY OF ASPIRATION AND ETHANOL INJECTION IN RECURRENT ENDOMETRIOMA BEFORE IVF CYCLE: A RANDOMIZED CLINICAL TRIAL. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 11(3), 179-184. SID. https://sid.ir/paper/295964/en

Vancouver: Copy

AFLATOONIAN ABASS, RAHMANI ELHAM, RAHSEPAR MOZHGAN. ASSESSING THE EFFICACY OF ASPIRATION AND ETHANOL INJECTION IN RECURRENT ENDOMETRIOMA BEFORE IVF CYCLE: A RANDOMIZED CLINICAL TRIAL. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2013;11(3):179-184. Available from: https://sid.ir/paper/295964/en

IEEE: Copy

ABASS AFLATOONIAN, ELHAM RAHMANI, and MOZHGAN RAHSEPAR, “ASSESSING THE EFFICACY OF ASPIRATION AND ETHANOL INJECTION IN RECURRENT ENDOMETRIOMA BEFORE IVF CYCLE: A RANDOMIZED CLINICAL TRIAL,” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 11, no. 3, pp. 179–184, 2013, [Online]. Available: https://sid.ir/paper/295964/en

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